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| 題 名 | 癌症晶片用於新藥開發與用藥指引之潛力=Exploring the Potential of Cancer Chips in Novel Drug Development and Clinical Drug Guidance |
|---|---|
| 作 者 | 林巧旻; 黃振煌; | 書刊名 | 科儀新知 |
| 卷 期 | 239 2024.06[民113.06] |
| 頁 次 | 頁42-53 |
| 專 輯 | 「器官晶片技術與應用」專題 |
| 分類號 | 448.65 |
| 關鍵詞 | 癌症晶片; 藥物開發; 免疫治療; 腫瘤微環境; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 癌症研究與治療之所以困難是因為腫瘤本身的微環境其複雜性極高,從早期藥物開發 到後期臨床用藥選擇都面臨種種挑戰。這歸咎於現有的體外或動物模型難以準確並再現這 種複雜情境,而癌症晶片的出現為解決這一困境帶來了希望。近期隨著晶片製造的技術突 破,這項技術逐漸成熟,並能夠更好地模擬腫瘤微環境。本文介紹癌症晶片的發展,以及 本團隊所開發的新技術,期望能在未來提供癌症相關研究和治療藥物開發新的選項。 |
| 英文摘要 | The complexity of cancer research and treatment is rooted in the intricate microenvironment of tumors. Challenges emerge at each phase, ranging from the initial stages of drug development to the process of selecting drugs for clinical application. This limitation arises from the challenges faced by existing in vitro or animal models in accurately reproducing this complex scenario. The development of cancer chips offers promise in addressing this challenge. Recent advancements in chip manufacturing have led to the maturation of technology that more accurately mimics the tumor microenvironment. This article presents the evolution of cancer chips and our team's novel technology, with the objective of providing innovative pathways for cancer research and the advancement of therapeutic drugs in the future. |
本系統中英文摘要資訊取自各篇刊載內容。