頁籤選單縮合
題名 | COVID-19疫苗簡介=A Brief Review of Three Coronavirus Disease 2019 (COVID-19) Vaccines |
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作者 | 蘇家彬; 陳孟妤; 顏嘉嫺; | 書刊名 | 疫情報導 |
卷期 | 37:7 2021.04.13[民110.04.13] |
頁次 | 頁86-95 |
分類號 | 412.42 |
關鍵詞 | COVID-19疫苗; Pfizer-BioNTech疫苗; Moderna 疫苗; AstraZeneca 疫苗; 疫苗保護力; 疫苗安全; COVID-19 vaccine; Pfizer-BioNTech vaccine; Moderna vaccine; AstraZeneca vaccine; Vaccine efficacy; Vaccine effectiveness; |
語文 | 中文(Chinese) |
中文摘要 | 快速發展的COVID-19疫苗,為控制疫情的重要工具之一。目前已上市的疫苗當中,病毒載體平台開發之AstraZeneca疫苗以及mRNA平台發展之Moderna與Pfizer-BioNTech疫苗,已在許多國家通過緊急授權,並進行大規模接種當中。就文獻資料來看,這三種疫苗無論是在上市前疫苗效力(vaccine efficacy)的評估,或是目前已施打的國家所做的疫苗效果(vaccine effectiveness)分析來看,接種疫苗後對於預防COVID-19感染、重症或死亡都能提供一定的保護力。疫苗接種後的不良事件以局部反應為多,嚴重不良事件比例極低。雖然疫苗的長期效果與安全性,以及對於病毒變異株的保護力,仍有待更多接種後的資料與評估,但就現階段資料來說,接種COVID-19疫苗益處大於風險,優先接種對象應儘早接種疫苗,以預防感染與重症的發生。 |
英文摘要 | One of the possible ways to end the SARS-CoV-2 pandemic is to develop COVID-19 vaccine and effective vaccination strategies. Some COVID-19 vaccines have been authorized for emergency use in a number of countries, and are currently in use around the world. These include an adenovirus-based vaccine (Astra-Zeneca), and two messenger RNA (mRNA) vaccines (mRNA-1273, manufactured by Moderna; BNT162b2, manufactured by Pfizer-BioNTech). These vaccines have been shown to be adequate in preventing SARS-CoV-2 infection, minimizing disease incidence, severity and mortality, according to current pre-licensure vaccine efficacy research and post-licensure vaccine effectiveness evaluations. Specific local reactions are common adverse reactions after receiving these vaccinations, and serious adverse events occur infrequently. However, more data is required after global vaccination to estimate long-term efficacy and protection in real-world condition, as well as the effects of vaccine against virus variants. Currently, the majority of studies indicate that vaccination protects people from COVID-19 and the benefits outweigh the risks. To reduce COVID-19-related morbidity and mortality, we encourage people who are prioritized in the immunization program to get vaccines as soon as possible. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。