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| 題 名 | 不同母乳添加劑劑型對於早產兒臨床預後差異之比較=Effects of Two Different Human Milk Fortifiers on Clinical Outcomes in Preterm Infants |
|---|---|
| 作 者 | 林鈺珊; 江明洲; | 書刊名 | 臺灣營養學會雜誌 |
| 卷 期 | 44:1 2020.03[民109.03] |
| 頁 次 | 頁18-25 |
| 分類號 | 411.374 |
| 關鍵詞 | 早產兒; 母乳營養強化; 餵食耐受不良; 生長速率; Preterm infants; Fortification of human milk; Feeding intolerance; Growth velocity; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 美國疾病管制中心建議在新生兒加護病房避免粉狀配方使用,目前台灣國內未引進液態母乳添加劑,故臨床上利用高濃度早產兒奶水強化母乳營養哺餵早產兒,以降低粉狀母乳添加劑感染風險。本回溯性病歷研究在探討粉劑與水劑等兩種不同母乳添加劑,對新生兒加護病房早產兒轉出體重、生長速率、禁食天數、代謝性酸中與壞死性腸炎等預後有無差異性。收集民國102年5月至103年8月間,出生體重小於2公斤之早產兒,篩選使用粉狀母乳添加劑組11位,與高濃度早產兒奶水強化母乳組12位。結果顯示高濃度早產兒奶水組,強化母乳營養餵食起始量顯著較低,轉出加護病房時的體重也顯著性較哺餵粉狀母乳添加劑者為重(p < 0.05),其餘數據則皆無顯著差異。本研究結果發現配合積極腸道餵食策略與密切監測生長相關營養指標,高濃度早產兒奶水與粉狀母乳添加劑相似,具良好的餵食耐受性,且不增加臨床副作用風險,可作為早產兒母乳添加劑選擇之一。 |
| 英文摘要 | Fortification of human milk with liquid concentrated preterm formula (LPF) was implemented in an effort to reduce risks of contamination and infection in a neonatal intensive care unit (NICU) as recommended by the Centers for Disease Control and Prevention (CDC). The purpose of this retrospective study was to compare clinical outcomes between preterm infants receiving a powdered human milk fortifier (PHMF) and receiving LPF. This retrospective study collected and evaluated growth parameters, nil per os (NPO) days, metabolic acidosis, late-onset infection, and the necrotizing enterocolitis (NEC) incidence of preterm infants with a birth weight of < 2 kg who received fortified human milk with either the PHMF (n = 11) or LPF (n = 12). Results revealed that the initial feed volume of fortified human milk was significantly lower and the body weight at discharge was significantly higher in the LPF group than the PHMF group (p < 0.05). Under a progressive enteral feeding strategy and close nutrition monitoring, fortified human milk with LPF was well tolerated and determined to be clinically safe for preterm infants in NICUs. |
本系統中英文摘要資訊取自各篇刊載內容。