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頁籤選單縮合
題名 | 海洛因成癮懷孕婦女之治療考量=The Consideration of Treatment for Pregnancy Women with Heroin Addiction |
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作者姓名(中文) | 李欣雅; 王治淦; 劉建宏; | 書刊名 | 藥學雜誌 |
卷期 | 35:3=140 2019.09[民108.09] |
頁次 | 頁2-7 |
分類號 | 415.8753 |
關鍵詞 | 海洛因; 懷孕; 美沙冬; 丁基原啡因; 納洛酮; 替代療法; |
語文 | 中文(Chinese) |
中文摘要 | 在台灣,目前最常用來當作海洛因替代療法的藥物為美沙冬 (methadone) 及丁基 原啡因 (buprenorphine) 併用納洛酮 (naloxone),它們可以減緩成癮者對於海洛因渴 求症狀以及減少停用海洛因之後的戒斷症狀,以防止成癮者再次使用毒品。對於海 洛因成癮之懷孕婦女來說,美國婦產科醫學會 (American College of Obstetricians and Gynecologist, ACOG) 認為 methadone 及 buprenorphine 為海洛因之維持療法主要藥 物。當懷孕婦女又為海洛因成癮者時,發生自發性流產的比例大約會是10%-20%。胎 兒出生後,更有高達55%-94%機會可能發生新生兒鴉片類物質戒斷症候群 (Neonatal Abstinence Syndrome, NAS)。於懷孕過程中,鴉片類物質成癮疾病的症狀會在中毒及 戒斷循環中不停發生,因此,懷孕婦女如有鴉片類物質成癮疾病對於本身及其胎兒都 是一種威脅。目前在國內,針對海洛因成癮懷孕婦女之維持療法藥物,methadone 仍 為首選治療藥物。 |
英文摘要 | In Taiwan, the most used drugs in maintenance treatments for heroin addiction are methadone and buprenorphine+ naloxone which can mitigate opioid cravings and withdrawal symptoms for abusers. American College of Obstetricians and Gynecologist recommends that methadone and buprenorphine monotherapy are commonly used for pregnant women with heroin addiction. About 10% to 20% of women with opioid dependence may have spontaneous abortion during pregnancy. Approximately 55% to 94% of exposed neonates develop neonatal abstinence syndrome. Opioid dependence is a continuous cycle of intoxication and withdrawal that poses a threat to both mother and fetus. At present, methadone is still the first line choice for pregnant women with heroin dependence. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。