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題 名 | 某區域醫院門診抗生素使用分析=Outpatient Antibiotic Use Evaluation in a Regional Hospital |
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作 者 | 楊紫麟; 陳秋榮; 李忠成; | 書刊名 | 藥學雜誌 |
卷 期 | 35:1=138 2019.03[民108.03] |
頁 次 | 頁121-126 |
分類號 | 418.281 |
關鍵詞 | 抗生素使用評估; 抗生素耗用量; 廣效性抗生素; |
語 文 | 中文(Chinese) |
中文摘要 | 目的:為了解個案醫院門診口服抗生素用藥情況,促進其合理應用,特對2016年1 月-2017年12月門診口服抗生素進行使用評估。 方法:以回溯性方式,使用院內資訊系統擷取2016年1月-2017年12月門診抗生素 處方,統計門診口服抗生素之處方佔率及總耗用量。抗生素耗用量的計算單位為「使 用密度」(DID)。本研究納入依世界衛生組織所公告藥品藥理治療分類 ATC 碼中 J01之 品項,包含第2,3代頭孢菌素、巨環類、蒽醌類藥物。除此之外進一步抽審兒科病人 病歷,分析其使用抗生素之理由及適當性。 結果:本研究中,2016年及2017年平均抗生素處方率分別為7.89%、6.77%。門診抗 生素之使用,以青黴素類選用排在第一位,其次是頭孢菌素類。在抗生素耗用量方面, 前三名包含 amoxicillin-clavulanate,amoxicillin 及 cefadroxil。觀察其開立科別:牙科最 常開立 amoxicillin,泌尿外科開立 cefadroxil 最多,兒科佔開立 amoxicillin-clavulanate 科別中的第1名。廣效性抗生素之使用亦以 amoxicillin-clavulanate 最多。此外,2017年 兒科病歷抽審其使用抗生素理由的合格率 (63.9%) 較2016年者 (48.7%) 進步。 結論:個案醫院門診口服抗生素使用率及廣效性抗生素 amoxicillin-clavulanate 耗 用量大的情形,於2017年皆較前一年改善;然仍需定期追蹤 amoxicillin-clavulanate 之 用藥合理性。 |
英文摘要 | Aims:This study aimed at evaluating oral antibiotic use in the outpatient setting for helping to optimize the treatment of infections. Methods:In a retrospective manner, this study obtained outpatient oral antibiotic prescribing data from January 2016 to December 2017 by the hospital information system and collected total consumption. The unit of antibiotic consumption, based on the Defined Daily Dose (DDD) of World Health Organization (WHO) announcement, is DID (DDD/1000 person-days). Using the Anatomical Therapeutic Chemical (ATC) code, antimicrobial agents of subgroup J01, part of anti-infectives for systemic use, were included. Broadspectrum antibiotics included second- and third-generation cephalosporins, macrolides, and fluoroquinolone. Medical records of pediatrics also had been reviewed by the pediatrician for analyzing the rationale of antibiotic prescribing. Results:The average antibiotic prescribing rates in 2016 and 2017 were 7.89 % and 6.77 %, respectively. The use of antibiotics was ranked first with penicillins, and followed by cephalosporins. Amoxicillin, amoxicillin-clavulanate, and cefadroxil were top 3 drugs consumed. Analysis by provider specialties was following: dentists prescribed amoxicillin most, urologists prescribed cefadroxil frequently, and pediatricians prescribed amoxicillinclavulanate more often. Regarding medical record review results, the rates of rational antibiotic use in the pediatric group were 48.7 % and 63.9 % in 2016 and 2017, respectively. Conclusions:In this study, oral antibiotic use in the outpatient setting is decreasing. The high use of amoxicillin-clavulanate, the broad-spectrum antibiotic consumed most in 2016, had a declining trend in 2017. However, the regularly tracking rational administration of amoxicillin-clavulanate should still go on. |
本系統中英文摘要資訊取自各篇刊載內容。