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題名 | Perianal Paget's Disease Associated with Anorectal Adenocarcinoma--Is Abdominoperineal Resection Necessary?=肛門周圍佩吉特氏病合併肛門腺癌--腹部會陰切除手術是必要的嗎? |
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作者 | 張玉樺; 蕭正文; 李家政; 吳昌杰; 饒樹文; | 書刊名 | 中華民國大腸直腸外科醫學會雜誌 |
卷期 | 28:4 2017.12[民106.12] |
頁次 | 頁217-220 |
分類號 | 416.245 |
關鍵詞 | 肛門周圍佩吉特氏病; 肛門腺癌; 腹部會陰切除手術; 術前放射治療; 廣泛性局部切除手術; Perianal Paget's disease; Wide local excision; Radiation therapy; Abdominoperineal resection; |
語文 | 英文(English) |
中文摘要 | 大約42%的肛門周圍佩吉特氏病會同時合併其他惡性腫瘤,且是一個重要的預後因子。因肛門周圍佩吉特氏病合併肛門腺癌的病例罕見,目前治療此類病患的方法有許多種,最常見的方式為腹部會陰切除手術。術前放射治療加上廣泛性局部切除手術對於肛門周圍佩吉特氏病合併肛門腺癌可能是一有效的治療方式,但是我們仍需要更多的病例及更長久的後續追蹤來證明。 |
英文摘要 | Case Report. A 65-year-old man was diagnosed as adenocarcinoma of anus and perianal Paget's disease (PPD) after biopsy of his anal tumor. The patient received neoadjuvant radiation therapy. Two months after radiation therapy, the patient received wide local excision under spinal anesthesia. The patient had no protective colostomy and no reconstructive flaps or skin graft. The patient discharged from our hospital 3 days later. We had followed the patient for one year and there was no recurrence or metastasis. Conclusions. About 42% of patients with PPD may have concurrent malignancies, and it is an important prognostic factor. Because of limited cases, the treatment of PPD with underlying anorectal carcinoma is diverse. Most of the patients was treated with abdominoperineal resection according to the staging system for perianal Paget's disease proposed by Kyriazanos et al. Neoadjuvant radiation therapy and wide local excision maybe an appropriate treatment in patients with PPD and localized anorectal carcinoma. However, we still need more cases and longer follow-up. |
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