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題名 | Application of a Fluorescence Visualization Loss System to Delimit the Resection Margin of Oral Cancer and Oral Precancer--A Serial Cases Report=螢光視覺衰退檢查系統於口腔腫瘤手術邊緣標定之應用--系列病例報告 |
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作者姓名(中文) | 邱聖富; 郭仕斌; 沈格祥; 蔣維凡; | 書刊名 | 臺灣口腔顎面外科學會雜誌 |
卷期 | 29:2 2018.06[民107.06] |
頁次 | 頁96-104 |
分類號 | 416.89 |
關鍵詞 | 螢光視覺衰退; 口腔癌; 手術邊緣; Autofluorescence visualization loss; Oral squamous cell carcinoma; Resection margin; |
語文 | 英文(English) |
中文摘要 | 口腔癌至今存活率仍然不佳且高居全球癌症盛行率第六位,對此,提高高危險族群病識感,早期篩檢,早期診斷和早期治療是面對此困境有效的策略。現行針對口腔癌甚至癌前病灶的篩檢策略主要依賴視診與觸診,並以黏膜切片作爲確診依據,然而對於第一線篩檢人員很難區分炎性組織與黏膜癌變的差異,甚至外科醫師在面對口腔癌與癌前病灶切除手術時也難以抉擇腫瘤邊緣何在。對此,近期許多診斷輔助工具被開發出來協助臨床人員應用於黏膜病變的偵測與手術邊緣之界定,其中螢光視覺衰退系統具有的優勢,包括即時性,可重複性與非侵犯性。本系列病例報告針對螢光視覺衰退系統運用在潛在性第二原發病灶與手術邊緣界定之協助進行分享,螢光視覺衰退系統輔助手術的未來性值得進一步大規模研究。 |
英文摘要 | Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide and still showed poor survival rate. The most effective way of combating this dilemma is raising awareness in high risk people, early detection, definite diagnosis and treatment. The current strategy for early detection of OSCC and oral precancers relied on visual and tactile examination followed by tissue biopsy for definite diagnosis. However, it is challenging for health workers to discriminate inflammatory reaction and cancerous changes, even detect some indolent lesions that lack the classic characteristic. Surgeons also face the similar scenario on demarcating the tumor burden when resecting the cancer and precancerous lesion. Recently, several diagnostic adjuncts have been developed to improve the management of oral cancer via early detection of the malignant lesions and better delimitation of the tumor margins. Fluorescence visualization loss (FVL) system has the characteristics of timeliness, reproducibility, noninvasiveness. The objective of this cases serial report was to share the experience of resection margin decision using FVL system. This report offered the potential value of large-scale study on FVL guided surgery. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。