頁籤選單縮合
題名 | Dexmedetomidine 於老年人之使用=Dexmedetomidine Use in Elderly Patients |
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作者 | 江俐慧; 蔡慈貞; | 書刊名 | 藥學雜誌 |
卷期 | 33:3=132 2017.09[民106.09] |
頁次 | 頁33-38 |
分類號 | 418.2131 |
關鍵詞 | 老年人; 鎮靜; 譫妄; Dexmedetomidine; |
語文 | 中文(Chinese) |
中文摘要 | 住進加護病房的老年人,譫妄發病率和死亡率較一般成年人明顯的增加。使用 dexmedetomidine (DEX) 和 benzodiaepines (BZDs) 相比,具有預防或治療加護病房譫 妄的潛力。DEX 提供有效的鎮靜、止痛和抗焦慮,而不引起呼吸抑制,使得病人能 更有效地與醫療團隊互動。這些有利的特質,減少整體鎮靜的持續時間和譫妄的發生 率,使得 DEX 成為預防或減少處於高風險的老年病人,於加護病房發生譫妄的可行 性選擇。於緩和醫療中,亦可用來輔助控制症狀和壓力。使用 DEX 而引起的血流動 力學不穩定,與較大的年齡及較低的基礎動脈血壓非常相關。本文藉由一臨床案例實 際情境,並以實證觀點來探討 DEX 用於老年人的相關因素。 |
英文摘要 | It’s an existing phenomenon that there was significantly higher the incidence of delirium and mortality for the elderly patients admitted to the intensive care unit (ICU) compared with the average adult. The use of dexmedetomidine (DEX) compared to benzodiaepines (BZDs) can be associated with the potential for the prevention or treatment of delirium in the ICU. DEX provided effective sedation, analgesia and antianxiety without causing respiratory depression and allowed the patients to interact more effectively with the medical team. These favorable traits reduced the overall duration of sedation and the incidence of delirium, making DEX a viable option for preventing or reducing the risk of delirium in the highrisk elderly patients in the ICU. In palliative care, DEX can also be used to help patients to control symptoms and stress. The risk factors of DEX induced hemodynamic instability were the older age and lower basic arterial blood pressure. Here, through a clinical case of the actual situation, the role of DEX used in the elderly will also be reviewed from an evidencebased point of view. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。