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頁籤選單縮合
題名 | Diffuse Large B Cell Lymphoma of the Maxilla--A Case Report=上顎瀰漫型大細胞淋巴瘤--病例報告 |
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作者 | 許彤年; 黃茂栓; | 書刊名 | 臺灣口腔顎面外科學會雜誌 |
卷期 | 28:2 2017.06[民106.06] |
頁次 | 頁137-149 |
分類號 | 416.954 |
關鍵詞 | 瀰漫型大細胞淋巴瘤; 口腔; 上顎; 潰瘍; 惡性腫瘤; Diffuse large B cell lymphoma; Oral cavity; Maxilla; Ulceration; Malignant tumor; |
語文 | 英文(English) |
中文摘要 | 淋巴癌是一種淋巴細胞的惡性腫瘤。它是第二常見的頭頸部惡性腫瘤,僅次於鱗狀細胞癌。一般來説惡性淋巴瘤可以被分類爲何杰金氏淋巴瘤及非何杰金氏淋巴瘤,而在口腔最常見的原發性非何杰金氏淋巴瘤爲瀰漫型大細胞淋巴瘤。一般常見之臨床表徵爲口腔出現局部性、伴隨疼痛感的糜爛潰瘍腫塊,類似於齒源性感染、囊腫、腫瘤,或是口腔惡性腫瘤的表現,常常因症狀相似而容易錯失一開始診斷的契機,導致不適當的診斷及後續治療。本文中我們將呈現一個於口腔右上顎出現局部潰瘍腫塊之64歲亞洲男性的病例,經由臨床及放射檢查發現此腫塊位於右侧上顎竇區域,併有右上顎區域齒槽骨破壞。切片結果證實爲瀰漫型大細胞淋巴瘤,後續安排轉診至血液腫瘤科進一步檢查及治療;病人在接受8次RCH0P化療後,治療的反應良好,腫塊明顯縮小。藉由此案例分享來説明早期發現、診斷及治療瀰漫型大細胞淋巴瘤的重要性。 |
英文摘要 | Lymphomas are malignant neoplasms of lymphoid cells. In the head and neck region, it is the second most common malignant tumor after squamous cell carcinoma. Lymphomas are generally classified into Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL). The most common type of primary oral NHLs is the diffuse large B cell lymphoma (DLBCL). The most, frequent symptom is a localized, painful, ulcerative swelling mass in the oral cavity which is similar to odontogenic infections, cysts or tumors, or even malignant lesions. It is easy to jump to wrong conclusions, resulting in inappropriate treatments. We present a case of a 64-year-old Taiwanese man with a localized, swelling, ulcerative mass in the right upper region of the oral cavity. Clinical and radiographic examinations showed a mass extending into right maxillary sinus with upper right alveolar ridge destruction. The biopsy report confirmed the diagnosis of DLBCL, and he was referred to division of Hematology and Oncology for further treatment. The patient was treated with 8 times chemotherapy (RCHOP) and the lesion responded well. The case demonstrates the importance of early detection, diagnosis and treatment to DLBCL. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。