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題名 | 利用磁敏感加權成像提升未施打顯影劑肝細胞癌之準確性=Susceptibility Weighted Imaging to Increase the Non-Contrast Diagnostic Accuracy of Hepatocellular Carcinoma |
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作者 | 陳文昌; 黃鈺湶; 林偉銘; 陳佳惠; 林松水; | 書刊名 | 中華放射線技術學雜誌 |
卷期 | 40:4 2016.12[民105.12] |
頁次 | 頁227-233 |
分類號 | 415.5362 |
關鍵詞 | 磁敏感加權成像; 肝細胞癌; 準確性; Susceptibility weighted imaging; Hepatocellular carcinoma; Accuracy; |
語文 | 中文(Chinese) |
中文摘要 | 磁敏感加權成像是磁振造影技術基礎上發展出來的一種新技術,有研究指出多次閉氣腹部磁敏感加權成像對檢測肝硬化病變含鐵結節的價值,亦發現磁敏感加權成像較常規的磁振造影序列檢出肝硬化含鐵結節數量和總量均明顯增高;此研究對於肝硬化病變基礎上,發生的再生結節、高低分化結節、小肝細胞癌和肝細胞癌的鑑別診斷十分重要。因此利用磁敏感加權成像能顯示肝細胞癌內小血管的數量、腫瘤內出血、病理新生血管及鈣化等,有助於評估腫瘤的良、惡性及分化程度。研究目的就是要利用磁敏感加權成像對血管與鐵沉積的敏感度,來針對肝細胞癌做鑑別診斷,以提升未施打顯影劑肝細胞癌診斷的準確性。所使用為3.0 T磁振造影儀器,共檢測60位疑似肝細胞癌患者,由二位放射科醫師分別對肝臟常規磁振造影影像、施打顯影劑後的三相式影像與磁敏感加權成像等3組影像進行鑑別診斷,其準確性分別為25.0%、95.0%及91.7%。經此研究證明磁敏感加權成像序列確實能利用它對血管與鐵沉積的敏感度,來診斷肝細胞癌。因此建議臨床,可增加使用此成像序列,以提升沒施打顯影劑肝細胞癌之準確性。 |
英文摘要 | Susceptibility weighted imaging (SWI) is a new imaging technique. Recent technical advances allow for possible abdominal applications and its role in the liver image study is still unclear. Based on the sensitivity to venous hemorrhage, iron deposition, and calcification, the breath hold abdomen MRI SWI sequence has been indicated valuable in the detection and quantification of iron nodules in liver cirrhosis patients. In order to increase the non-contrast diagnostic accuracy of hepatocellular carcinoma, the purpose of this study is to compare the susceptibility weighted to conventional non-contrast and tri-phase contrast enhancement liver MRI imagings. Total of sixty cases with highly suspected hepatocellular carcinoma (HCC) were recruited and examined by 3.0T MRI technology in this study. For qualitative analysis, the HCC was assessed for diagnostic sensitivity. The three groups of images were evaluated by two radiologists. The diagnostic sensitivities of non-contrast-enhanced conventional, 2D SWI, and tri-phase contrast-enhanced MRI were 25.0%, 95.0%, and 91.7%, respectively. We suggest that non-contrast conventional MRI combined with 2D SWI MRI sequence can improve the diagnostic accuracy of HCC patients. |
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