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頁籤選單縮合
題名 | 新生兒呼吸窘迫症候群介紹=Introduction of Respiratory Distress Syndrome |
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作者姓名(中文) | 林廷澔; | 書刊名 | 藥學雜誌 |
卷期 | 32:4=129 2016.12[民105.12] |
頁次 | 頁55-60 |
分類號 | 417.53 |
關鍵詞 | 呼吸窘迫症候群; 表面張力素; 產前類固醇; |
語文 | 中文(Chinese) |
中文摘要 | 新生兒呼吸窘迫症候群 (respiratory distress syndrome;RDS) 是早產兒最常見的疾 病。由於胎兒早產,肺部尚未發育成熟和肺表面張力素 (surfactant) 分泌不足,致使 肺無法正常擴張,因此胎兒產生呼吸急促 (tachypnea)、發紺 (cyanosis) 等症狀。疾病 依照胸部X光的變化可以分成四級,級數越高越嚴重。 RDS 最好的預防方法是避免早產,若無法避免,建議在妊娠週期23-34週,且未 來7天內有可能生產者,給予產前類固醇。產前類固醇可以促進胎兒肺部發育且增進 表面張力素的分泌。 RDS 在治療上,除了儘早使用持續性呼吸性正壓呼吸器 (continuous positive airway pressure;CPAP) 之外,給予外生性表面張力素,也可以有效降低新生兒的死 亡率。 |
英文摘要 | Respiratory distress syndrome, RDS, is the most common disease in preterm neonate. The syndromes of the disease are coming from immature lung function and insufficient lung surfactant secretion, because of preterm laboring. The lung of these preterm neonates will not be able expanding normally. This will lead to respiratory distress. The common syndromes are tachypnea, grunting and cyanosis etc. Base on the chest X-ray image, the disease can classify to four grades, grade one to four. The higher the grade is, the more severe the disease is. The best way to prevent RDS is avoiding preterm laboring. If preterm delivering cannot be avoided, it is recommending to administration of antenatal corticosteroid therapy, especially on women at risk of preterm delivery in seven days from about 23 weeks up to 34 completed week gestation. Antenatal corticosteroid therapy can facilitate the fetal lung development and increase the secretion of surfactant. In the treatment of RDS, it is recommending to use continuous positive airway pressure, CPAP, as soon as possible. At the same time, once RDS is confirmed, exogenous surfactant should give to the preterm neonate right away. The surfactant therapy can decrease the mortality of the preterm neonate. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。