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題 名 | Metastatic Adenocarcinoma of the Mandible and Gingiva from the Uterus--A Case Report=原發於子宮之下顎骨及牙齦轉移性腺癌--病例報告 |
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作 者 | 余玲敏; 許文瑛; 許恆誠; 李正喆; 張廷禎; | 書刊名 | 臺灣口腔顎面外科學會雜誌 |
卷 期 | 27:4 2016.12[民105.12] |
頁 次 | 頁286-295 |
分類號 | 416.954、416.954 |
關鍵詞 | 口腔轉移性惡性腫瘤; 子宮頸癌; 下顎骨; Oral metastases; Cervical cancer; Mandible; |
語 文 | 英文(English) |
中文摘要 | 轉移至骨頭之婦科惡性腫瘤相當罕見。本病例爲一67歲女性,經診斷爲轉移至下顎骨及牙齦之第一級,IVB階段之子宮頸癌。患者因左下後牙疼痛就診,初步診斷爲牙周病。然而拔牙傷口癒合困難,故轉至台大醫院就診。由於惡性病灶無法排除,於是在局部麻醉下接受切片檢查。病灶病理切片顯示被完整分化腺癌浸潤之牙齦及骨碎片。病患隨後接受經腹腔子宮切除及雙側輸卵管卵巢切除,以及化學輔助性治療。然而在診斷後兩個月病患仍因多重器官轉移過世。根據先前研究亦顯示轉移至口腔病灶之預後差,兩年内生存率低。而此類型疾病經常難以作出正確診斷,病理切片爲此類疾病最標準的診斷工具。 |
英文摘要 | Bone metastases from gynecologic malignancies are very rare. Here we present a case of a 67-year-old woman with grade 1, stage IVB cervical cancer who had a metastasis to the mandible. She felt pain over left lower posterior teeth, and was diagnosed as periodontitis. But the extraction sockets healed poorly. Then she visited our hospital for help. Due to malignancy was highly suspected, incisional biopsy was done under local anesthesia. The pathologic results of mandibular lesion showed gingiva and bone fragments with infiltration of well differentiated adenocarcinoma. She was treated with a trans- abdominal hysterectomy and bilateral salpingo-oophorectomy and adjuvant chemotherapy but after 2 months of primary diagnosis, she deceased due to multiple organ metastases. Oral metastases has poor grade prognosis. The 2-year survival rate after initial diagnosis of oral metastases is low. These kinds of cases usually encounter the difficulty in diagnosis, and histopathology is always the most important diagnostic method. |
本系統中英文摘要資訊取自各篇刊載內容。