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題名 | 手術前後抗凝血劑停藥原則=Perioperative Management of Patients Receiving Anticoagulants |
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作者姓名(中文) | 劉敏俐; 簡麗卿; 洪永潤; 林梅芳; 陳思穎; | 書刊名 | 藥學雜誌 |
卷期 | 32:1=126 2016.03[民105.03] |
頁次 | 頁86-91 |
分類號 | 418.2321 |
關鍵詞 | 手術期間; 抗凝血劑; 血栓栓塞; Perioperative; Thromboembolism; Anticoagulants; |
語文 | 中文(Chinese) |
中文摘要 | 臨床上使用抗凝血劑患者在面臨手術時是否停藥、停藥多久、術後多久回復抗凝 血劑的使用,都是一個重要的議題。中斷抗凝血劑使用,可能增加栓塞風險;未中斷 抗凝血劑使用,同時接受手術或侵入式診斷治療,可能增加出血風險1。隨著新型抗 血劑的問世,不同於傳統抗凝血劑 (warfarin),其具更快的起始作用與更短的作用時 間,因此須衡量不同抗凝血劑的藥物動力學。在臨床決策上,衡量個別患者栓塞與出 血風險,決定是否停用抗凝血劑或理想的停藥時機。 |
英文摘要 | Receiving surgery is a challenging issue for patients on anticoagulant therapy. Interrupting anticoagulation for a procedure transiently increases the risk of thromboembolism, whereas maintaining anticoagulation during surgery and invasive procedures entails associated bleeding risks. Unlike traditional anticoagulants (Warfarin), new anticoagulants have a more rapid onset and shorter half-lives. Establishing a balance between a reduction of the risk of thromboembolism and the prevention of excessive bleeding requires careful evaluation for each patient on anticoagulant therapy, taking pharmacokinetics into account. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。