頁籤選單縮合
題名 | 急性腎損傷之生物標誌=Biomarkers of Acute Kidney Injury |
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作者姓名(中文) | 范佩君; 張智翔; 陳永昌; | 書刊名 | 腎臟與透析 |
卷期 | 27:4 2015.12[民104.12] |
頁次 | 頁167-172 |
專輯 | 重症腎臟學專輯 |
分類號 | 415.74 |
關鍵詞 | 急性腎損傷; 急性腎衰竭; 生物標誌; Acute kidney injury; Acute renal failure; Biomarker; |
語文 | 中文(Chinese) |
中文摘要 | 近年來儘管研究蓬勃發展、醫療水準大幅提升,急性腎損傷仍舊合併相當高的罹病率和死亡率。傳統以血清肌酸酐為依據的診斷標準,存在無法早期診斷的盲點。新興生物標誌的發展,例如嗜中性白血球明膠酶相關性脂質運載蛋白(NGAL)、腎損傷分子1 (KIM-1)、第十八型細胞間素(IL-18)及血清胱蛋白C (cystatin C)等,除了幫助我們更加瞭解急性腎損傷的複雜病生理機轉,也有助於早期診斷、及時介入治療,甚而改善病人的預後。 |
英文摘要 | Over the past decades, despite advanced progress in research and medical, acute kidney injury is still associated with significant morbidity and mortality. Traditional diagnostic criteria of acute kidney injury is based on serum creatinine, which is not a reliable indicator during acute changes of kidney function. Novel biomarkers such as NGAL, KIM-1, IL-18 and cystatin C allow us to unravel the complex pathophysiology of acute kidney injury, and more importantly, to provide the chance of early diagnosis and timely treatment. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。