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| 題 名 | 以血管內超音波及血流儲備分數評估冠狀動脈定量分析中度狹窄病灶結果之差異性=The Difference of Evaluation Result in Intermediate Lesion by Quantitative Coronary Angiography, Intravascular Ultrasound and Fractional Flow Reserve |
|---|---|
| 作 者 | 羅正一; 郭瓊文; 陳渙東; 李仁忠; 王仁享; 侯佳听; 楊迺慈; | 書刊名 | 臺灣應用輻射與同位素雜誌 |
| 卷 期 | 9:2 2013.06[民102.06] |
| 頁 次 | 頁653-660 |
| 分類號 | 415.2168 |
| 關鍵詞 | 血流儲備分數; 血管內超音波; 冠狀動脈定量分析; 中度狹窄病灶; FFR; IVUS; QCA; Intermediate lesion; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 本研究針對冠狀動脈定量分析所診斷出來中度狹窄病灶的病患,做血管內超音波(IVUS)與血流儲備分數(FFR)的驗證,透過IVUS與FFR的結果針對中度狹窄病灶是否有必要進行冠狀動脈介入治療,其FFR與IVUS的觀點是否一致。本研究收集20位冠狀動脈定量分析所診斷出來中度狹窄病灶的病患,並以血管內超音波分析每位病患血管狹窄的位置並和其狹窄血管所量測到的血流儲備分數做比較,來驗證三種測量方法之間的一致性。病灶的長度(lesion length, LL)、直徑狹窄率(percent diameter stenosis, PDS)與面積狹窄率(percent area stenosis, PAS)與FFR值有負相關的現象存在,而最小管腔面積(minimal lumen area, MLA)及最小管腔直徑(minimal lumen diameter, MLD)數值與FFR值有正相關的關係,但是相關性較強的只有MLA、PDS與PAS。根據此現象取得MLA的截取值為2.9 mm^2,PDS為38.2 %,PAS為58.8 %。本研究經由QCA、IVUS與FFR的分析比較,得出結構性狹窄與功能性狹窄的交集,MLA的截取值只要在2.9 mm^2之上、直徑狹窄率的截取值在38.2 %以下以及面積狹窄率的截取值在58.8 %以下,其FFR值就會在0.8以上。 |
| 英文摘要 | The aim of this study was to assess the relationship among QCA, IVUS and FFR in coronary artery with intermediate lesion. We assessed the relationship among QCA, IVUS, and FFR in 20 patients. By using IVUS, we demonstrated the cutoff value of percent area stenosis (PAS) was 58.8 %, percent diameter stenosis (PDS) was 38.2 %, and minimal lumen area (MLA) was 2.9 mm^2 in intermediate coronary stenosis with FFR value < 0.8. These findings suggested that coronary intervention might not be proceed while the values of MLA, PAS and PDS were under these cutoff values. |
本系統中英文摘要資訊取自各篇刊載內容。