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題名 | SAFIRE Improves CT Image Quality in PET/CT Scans: An ACR CT Phantom Test=SAFIRE疊代式影像重建法改善PET/CT中CT影像品質:ACR CT假體實驗 |
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作者 | 柴發順; 王素貞; 周宣宏; 江泰林; 歐玲君; Tsai, Fa-shun; Wang, Su-chen; Chou, Hsuan-hung; Jiang, Tai-lin; Ou, Lin-chun; |
期刊 | Annals of Nuclear Medicine and Molecular Imaging |
出版日期 | 20140300 |
卷期 | 27:1 2014.03[民103.03] |
頁次 | 頁3-11 |
分類號 | 414.93 |
語文 | eng |
關鍵詞 | 電腦斷層; 疊代; 影像重建; CT; Iterative reconstruction; PET/CT; SAFIRE; |
中文摘要 | 背景:PET/CT是結合CT解剖影像與PET功能性影像的影像檢查,CT影像提供了PET衰減修正的資訊也提供解剖位置資料並作為輔助診斷的參考。PET/CT檢查掃描範圍大,考慮受檢者所受輻射劑量多以較低管電流的低劑量CT條件進行常規掃描。本實驗目的在不同CT管電流條件下PET/CT掃描資料以SAFIRE影像重組法與濾波反投影法FBP分別重組影像,比較兩種不同影像重組法獲得的CT影像差異。方法:將ACRCT假體放置於Siemens Biograph mCT PET/CT掃描儀中進行PET/CT掃描,CT掃描條件比照常規PET/CT檢查,以140、120、100、80、60、40和20 mAs進行掃描。所有掃描資料分別以FBP及SAFIRE strengths 1、3和5進行影像重組。各組影像以Gammex 464-Automated CT software進行自動分析比較:CT數值測試、雜訊測試、影像均勻度、空間解析度、對比雜訊比、雜訊測試。結果:在各個不同的CT劑量條件下,SAFIRE影像重建法與FBP重建的影像,在CT數值測試、空間對比度與影像均勻度測試皆通過ACR測試要求,且無明顯差異。在相同CT劑量條件下,SAFIRE重建的影像都比FBP影像有更低的雜訊及更高的對比雜訊比。SAFIRE filter strength 1、3、5的影像雜訊平均為在同樣CT劑量條件下FBP影像的89.64%,68.97%,49.21%;對比雜訊比為FBP影像的112.35%,162.50%,210.00%。以140m As條件FBP影像為標準,SAFIRE filter strength 3影像只需要60m As的CT劑量條件即可達到相同的對比雜訊比及雜訊程度。結論:常規PET/CT掃描多採用低劑量條件CT進行掃描。SAFIRE影像重建法可在保持空間解析度下降低影像雜訊並提升對比雜訊比,提供更好的影像品質,幫助醫師獲得更多診斷資訊。 |
英文摘要 | Background: PET/CT is a hybrid scanner that offers CT anatomic and PET functional information of a patient within a single examination. In addition, the CT images can be used to correct PET scans for photon attenuation and for diagnosis reference. Considering about the patient protection, low-dose CT is usually chosen in the PET/CT examinations. The purpose of this study is to evaluate the effect of the sonogram affirmed iterative reconstruction (SAFIRE) algorithm on image quality, compared with filtered back projection (FBP) by American College of Radiology (ACR) phantom in PET/CT scans.Methods: An ACR accreditation phantom (model 464, Gammex-RMI, Middleton, WI) was scanned with Siemens Biograph mCT PET/CT scanner. CT scanning parameters were as routine PET/CT scan with various mAs (140, 120, 100, 80, 60, 40 and 20 mAs). Images were reconstructed with both FBP and multiple values of SAFIRE filter strengths 1, 3 and 5. All images were automatically analyzed by Gammex 464-Automated CT software to avoid individual differences.Results: In phantom study, CT number test, high contrast resolution and uniformity assessments showed no significant difference between SAFIRE or FBP reconstruction. However SAFIRE improves image noise and contrast to noise ratio significantly. Compared with FBP, the mean image noises with SAFIRE filter strength 1, 3 and 5 were 89.64%, 68.97% and 49.21%, respectively. Additionally, the mean CNRs were 112.35%, 162.50% and 210.00%, respectively. At 60 mAs SAFIRE filter strength 3, the noise level and Contrast to Noise Ratio (CNR) were equivalent to 140 mAs FBP image.Conclusion: This study shows that SAFIRE applied to low-dose CT can significantly reduce noise and increase contrast noise ratio when compared with standard FBP at higher dose levels. SAFIRE image reconstruction method showing better CT image quality than FBP in the low-dose CT conditions can provide more diagnostic information. |
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