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頁籤選單縮合
| 題 名 | 加護病房壓力性潰瘍的預防=Prevention of Stress Ulcer in Intensive Care Unit |
|---|---|
| 作 者 | 項怡平; | 書刊名 | 藥學雜誌 |
| 卷 期 | 30:4=121 2014.12[民103.12] |
| 頁 次 | 頁27-30 |
| 分類號 | 415.526 |
| 關鍵詞 | 加護病房; 壓力性潰瘍; 呼吸器插管; 凝血病變; Stress ulcer; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 75-100%的病人在住進加護病房 (intensive care unit, ICU) 24小時之內會有壓力所 造成的黏膜受損 (stress-related mucosal disease, SRMD),其中 1.5-8.5%的病人會出現腸 胃道出血,嚴重者需要輸血治療,增加死亡率也延長住院天數。而主要造成加護病房 壓力性潰瘍的2大風險因素為呼吸器插管超過48小時,及凝血病變,因此在美國健康 體系藥師學會中 (American Society of Health System Pharmacists) 建議,具有胃腸重大 出血風險因素的加護病房病人,應投予預防壓力性潰瘍 (stress ulcer prophylaxis, SUP) 藥品。本文討論預防壓力性潰瘍藥品的適當選擇,有助於藥師進行加護病房藥事照護 時能提供醫師選擇正確的藥品。 |
| 英文摘要 | Endoscopic studies have since identified that between 75-100% of critically ill patients have stress-related mucosal erosion within 24 hours of admission. Estimate of the incidence of overt GI bleeding range from 1.5 to 8.5% among all intensive care unit (ICU) patient. Clinically important GI bleeding can cause hemodynamic instability and increase the need for red blood cell transfusion. Significant bleeding may also increase the length of stay in the ICU and mortality. Two major independent risk factors for clinical important GI bleeding due to stress ulcer are mechanical ventilation for more than 48hours and coagulopathy. American Society of Health System Pharmacists recommends stress ulcer prophylaxis should be administered to the critically ill patients who are at high risk for GI bleeding. This article discusses the appropriate selection agents of stress ulcer prophylaxis, then pharmacists can provide for physicians choices of the right drug during the ICU pharmaceutical care service. |
本系統中英文摘要資訊取自各篇刊載內容。