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頁籤選單縮合
題名 | 高齡者門診用藥之藥物交互作用=Drug-Drug Interactions in Elder Patients Presenting to an Outpatient Clinic |
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作者 | 楊瑛碧; 鮑柏穎; 鮑俊蓓; | 書刊名 | 北市醫學雜誌 |
卷期 | 11:2 2014.06[民103.06] |
頁次 | 頁135-145 |
分類號 | 418.1 |
關鍵詞 | 老人; 門診處方用藥; 潛在嚴重藥物交互作用; Elderly; Outpatient prescriptions; Potentially serious drug interactions; |
語文 | 中文(Chinese) |
中文摘要 | 探討門診老年用藥常發生藥品交互作用之種類,以提高醫療人員開立藥品之警覺,共同保障病人用藥安全。方法:回溯性觀察收集2011年1-6月間至門診就醫65歲以上老人處方用藥資訊,並以院內資訊系統內建之藥品交互作用資料、Micromedex及MIMS交互作用查詢系統協助篩選發現一級或二級藥品交互作用。結果:研究發現65歲以上老人診斷多為慢性疾病。門診用藥一張處方平均藥品數為4.8種,最多開立14種藥品,仍有高達21.7%門診處方大於5種藥物使用。嚴重藥物交互作用佔3.7%,中等程度藥物交互作用佔55.6%,需謹慎使用藥物交互作用佔9.5%。結論:門診藥物交互作用系統,可以藉由資訊設定,協助提示開立處方醫師判斷,避免因嚴重藥物交互作用,發生藥物副作用及不良反應。 |
英文摘要 | To investigate the degree of drug-drug interaction among elderly outpatients in our hospital clinics. This should increase the vigilance of medical staffs when dispensing drugs for elderly outpatients and ensure safe drug use. Methods: We retrospectively collected prescription information from elderly outpatients during January to June 2011. Through the in-house drug-drug interaction information system, Micromedex, and MIMS drug interaction query system, we filtered out the records of primary and secondary drug interactions. Results: Elderly outpatients were frequently diagnosed with chronic diseases. The average number of drugs per outpatient prescription was 4.8, and up to 14 drugs in one prescription. A total of 21.7% of outpatients were prescribed more than 5 kinds of drugs. More importantly, 3.7% of the outpatient prescriptions had serious drug interactions. The rates of moderate and mild drug-drug interaction were 55.6% and 31.2%, and 9.5% of the prescriptions were marked use with caution. Conclusion: Outpatient drug-drug interaction information systems could provide prescribing suggestions for physicians to avoid inappropriate drug combinations and adverse reactions due to drug interactions for elderly patients. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。