頁籤選單縮合
題名 | 疑似原發性腎病症候群之案例=A Case of Suspected Idiopathic Nephrotic Syndrome |
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作者姓名(中文) | 康建文; | 書刊名 | 藥學雜誌 |
卷期 | 30:2=119 2014.06[民103.06] |
頁次 | 頁85-90 |
分類號 | 417.574 |
關鍵詞 | 兒童腎病症候群; 微小腎病變; Childhood nephrotic syndrome; Minimal change disease; MCD; |
語文 | 中文(Chinese) |
中文摘要 | 「腎病症候群」是由於腎病變造成腎絲球通透性增加,導致大量血漿蛋白透過尿 液流失。臨床上典型症狀包括低白蛋白血症 (血漿 albumin 小於3.0 g/dL)、尿蛋白每 天排出大於3.5 g、水腫以及高脂血症 (尤其是膽固醇 > 200 mg/dL)。原發性腎病症候 群常見於六歲以下兒童,其中又以微小變化型 (minimal change disease, MCD) 最為常 見。此類型大多對類固醇治療反應良好,然而,療程往往需要服用數週以上,因此對 於早期症狀的控制很重要的。尤其當反應不佳時,故本文試由病歷分析,探討原發性 腎病症候群的成因、預後與治療指引,做為藥學訓練小兒科教學之教案。 |
英文摘要 | Nephritic syndrome (NS) is a condition caused by renal diseases that increase the permeability across the glomerular filtration barrier, resulting in the loss of lots protein from blood into urine. In clinical, it is classically characterized by four features including hypoalbuminemia (serum albumin concentration < 3.0 g/dL)、nephrotic range proteinuria (excretion greater than 3.5 g/day)、edema and hyperlipidemia (especially cholesterol > 200 mg/dL). Primary or idiopathic nephritic syndrome (NS) is more common in younger children, particularly those less than six years of age and in them the minimal change disease (MCD) is the most common cause. In this type, the majority of childhood nephritic syndrome will respond well to steroid, however, symptomatic management is important in the early course of therapy as response to steroid therapy may take several weeks and it is the mainstay of therapy in children who fair to respond to steroid. Therefore, this paper attempts to analysis the case and explores the causes、prognosis and treatment guideline about nephrotic syndrome to be a pediatric teaching plan for training pharmacy students. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。