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題名 | Positron Emission Tomography/Computed Tomography False Positivity for Xanthogranulomatous Inflammation in an Adolescent with Hodgkin's Lymphoma=罹患何杰金氏淋巴瘤青少年以正子電腦斷層攝影偽陽性為表現的黃色肉芽腫性發炎 |
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作者 | 俞瑞庭; 滕傑林; 林瑛珠; 王任卿; 黃文豊; | 書刊名 | 臺灣癌症醫學雜誌 |
卷期 | 1:1 2014.06[民103.06] |
頁次 | 頁50-56 |
分類號 | 415.6 |
關鍵詞 | 何杰金氏淋巴瘤; 正子電腦斷層攝影; 偽陽性; Hodgkin's lymphoma; PET/CT; False positivity; |
語文 | 英文(English) |
中文摘要 | 雖然正子電腦斷層攝影對何杰金氏淋巴瘤的分期及評估治療反應為一相當敏感的工具,但針對早期發現疾病復發的角色仍無定論。因正子電腦斷層攝影用於常規追蹤時有 較高的偽陽性,容易導致已有完全緩解的患者接受不必要的治療。我們報告的病例是一 位 15 歲少年,於接受正子電腦斷層攝影追蹤時發生了偽陽性。腫瘤減積手術的病理報告 發現有黃色肉芽腫性發炎(xanthogranulomatous inflammation)、纖維化、陳舊出血、及胸 腺與肋膜的纖維沾黏,但卻沒有殘餘癌細胞。經手術一年後,該患者仍恢復良好、沒有 疾病復發的跡象。這個病例說明了正子電腦斷層攝影用於治療後已達完全緩解的何杰金 氏淋巴瘤患者追蹤時可能發生偽陽性,因此組織切片仍是何杰金氏淋巴瘤患者在確認疾 病復發時的主要依據。 |
英文摘要 | Although positron emission tomography/computed tomography (PET/CT) is a sensitive tool for Hodgkin’s lymphoma (HL) staging and response evaluation, its role in early detection of disease relapse remains controversial. A high false positivity of routine PET/CT during follow-up may result in unnecessary treatment of HL patients who are in complete remission. Here we report a 15-year-old boy who had a false positive PET/CT result during his follow-up. Debulking surgery was performed for the suspicious lesion, which showed xanthogranulomatous inflammation, fibrosis, old hemorrhage and fibrous adhesion of thymic tissue and pleura, but no residual tumor cells. One year after the surgery, this patient remained well without any evidence of disease relapse. Our case shows that PET/CT could provide false positive imaging in HL patients who are in complete remission after treatment. Tissue biopsy remains the really necessary tool of confirming disease relapse in patients with HL. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。