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題名 | 危急性肢體缺血的臨床處理=Management of Critical Limb Ischemia |
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作者 | 江俐慧; 陳琦華; 鄧新棠; Chiang, Li-huei; Chen, Chi-hua; Deng, Shin-tarng; |
期刊 | 藥學雜誌 |
出版日期 | 20130600 |
卷期 | 29:2=115 2013.06[民102.06] |
頁次 | 頁82-85 |
分類號 | 416.263 |
語文 | chi |
關鍵詞 | 危急性肢體缺血; 周邊動脈阻塞疾病; 血栓溶解劑; 前列腺素; |
中文摘要 | 危急性肢體缺血是一個周邊動脈疾病進展到疾病末期的表現。由於不適當的肢體血流,導致病人休息疼痛、肢體潰瘍或壞疽。罹患周邊動脈疾病的病人,約1-3%會惡化成危急性肢體缺血。診斷出危急性肢體缺血的病人,一年的死亡率高達25%,30%的病人須作重大的截肢手術以保全性命。臨床上,這樣的病人急迫地需要立即以血管重建術來處理。本文藉由一案例的臨床實際情境,並以實證的觀點探討血栓溶解劑及前列腺素,在危急性肢體缺血治療中所扮演的角色。 |
英文摘要 | Critical limb ischemia (CLI) is considered the "end stage" of peripheral artery disease (PAD). CLI is a manifestation of rest pain, limb ulcers or gangrene due to inappropriate limb blood flow. Patients with CLI represent approximately 1-3% patients with PAD. About 25% of patients will have died within one year after diagnosis and a further 30% will suffer a major amputation to save their lives. Treatment for CLI often requires prompt revascularization. Here we will report a real CLI case scenery. The roles of antithrombotic drugs and prostaglandin E1 in CLI will also be reviewed from an evidence-based point of view. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。