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題名 | Eosinophilic Esophagitis: Report of a Case=嗜伊紅性白血球食道炎:一病例報告 |
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作者姓名(中文) | 陳武峻; 蔡明杰; 吳毅穎; 江技坤; 賴永智; 吳啟華; | 書刊名 | 臺灣消化醫學雜誌 |
卷期 | 30:1 2013.03[民102.03] |
頁次 | 頁20-24 |
分類號 | 415.511 |
關鍵詞 | 嗜伊紅性白血球食道炎; 吞嚥困難; 食物哽塞; Eosinophilic esophagitis; Dysphagia; Food impaction; |
語文 | 英文(English) |
中文摘要 | 以食道功能障礙和食道黏膜嗜伊紅性白血球浸潤為主要表現的嗜伊紅性白血球食道炎是罕見的疾病,我們提出一個對固態食物出現漸進式吞嚥困難並伴隨輕微胸痛一個月的40歲男性病例,上消化道內視鏡顯示廣泛分布的同心圓環,縱向皺紋和白色的滲出液斑塊。實驗室數據顯示有比較高的IgE免疫球蛋白,但是週邊血液並沒有伴隨嗜伊紅性白血球的增加。病理組織切片顯示食道黏膜有明顯的嗜伊紅性白血球浸潤(>15高倍率視野下)。因此診斷為嗜伊紅性白血球食道炎,該病人對質子幫浦阻斷劑沒有反應,在病人開始服用口服類固醇後吞嚥困難的症狀獲得漸漸的改善。嗜伊紅性食道炎是造成成人吞嚥困難的原因之一,這篇文章所提出的病例重點主要是呈現嗜伊紅性食道炎的病人在臨床、內視鏡與組織病理的特徵。 |
英文摘要 | Eosinophilic esophagitis (EoE) is a rare disorder characterized by symptoms of esophageal dysfunction and marked eosinophilic infiltration of esophageal mucosa. We present a 40-year-old male who suffered from progressive dysphagia with solid food and mild chest pain for 1 month. Upper endoscopy revealed diffuse concentric rings, longitudinal furrows and adherent white exudates. Laboratory data showed elevated total IgE but without peripheral blood eosinophilia. Histopathology of the biopsy specimen of the esophageal mucosa showed prominent intraepithelial eosinophilic infiltration (>15/HPF). Under the diagnosis of eosinophilic esophagitis, the symptoms were non-responsive to proton pump inhibitor therapy, oral steroids were prescribed and the dysphagia improved gradually. EoE is a distinct cause of dysphagia and food impaction in adults. Our present case highlights the clinical and endoscopic features, histopathological criteria and response to medical treatment. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。