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題 名 | Pulmonary Alveolar Proteinosis Combined with Pulmonary Aspergillosis in an Elderly Patient: A Case Report and Literature Review=老年病人肺泡蛋白沉積症合併肺麴菌感染:病例報告與文獻回顧 |
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作 者 | 鄒秉諴; 傅彬貴; 陳奕先; 沈光漢; 許正園; | 書刊名 | 胸腔醫學 |
卷 期 | 28:1 2013.02[民102.02] |
頁 次 | 頁18-24 |
分類號 | 415.46 |
關鍵詞 | 肺泡蛋白沉積症; 麴菌; 長期呼吸器依賴; Pulmonary alveolar proteinosis; Aspergillosis; Long-term ventilator dependence; |
語 文 | 英文(English) |
中文摘要 | 肺泡蛋白沉積症是一種罕見的疾病。此疾病與肺表面活性劑在肺部累積,肺泡巨噬細胞失能有關,導致呼吸困難與肺部免疫機能缺失。此疾病診斷的平均年齡為42歲,老年人的肺泡蛋白沉積症並不常見。老年人常見的併發症包括嚴重呼吸衰竭與繼發機會性感染。我們報告一個74歲的肺泡蛋白沉積症病人,合併嚴重低血氧呼吸衰竭與肺麴菌感染。病人在抗麴菌治療後,接受了單側循序性的全肺灌洗,成功的治療了呼吸衰竭,並脫離了長時間依賴的呼吸器。 |
英文摘要 | Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the accumulation of surfactant lipids and proteins in the alveoli of the lungs, leading to respiratory insufficiency and alveolar macrophage dysfunction. The median age at diagnosis is 42 years. It is uncommon in the elderly and has a high morbidity, mainly from respiratory failure and infection. We report the case of a 74-year-old female diabetic patient with PAP and pulmonary aspergillosis complicated by severe hypoxemic respiratory failure and long-term ventilator dependence. The hypoxemia was resolved, lung infiltrates reduced, and the patient was weaned from the ventilator after successful anti-fungal therapy and sequential unilateral whole lung lavage. |
本系統中英文摘要資訊取自各篇刊載內容。