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題名 | Radiation-induced Osteosarcoma of the Temporal Bone=放射線引發之骨肉瘤 |
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作者 | 許永信; 容世民; 張文震; 張兗君; | 書刊名 | 臺灣癌症醫學雜誌 |
卷期 | 28:3 2012.09[民101.09] |
頁次 | 頁134-139 |
分類號 | 416.66 |
關鍵詞 | 放射線引發之骨肉瘤; 顱骨腫瘤; Radiation-induced sarcoma; Skull tumor; |
語文 | 英文(English) |
中文摘要 | 32 歲女性,4 年前曾因腦室神經細胞瘤接受放射治療,發現右顳部腫起。腦部電腦 斷層及核磁共振都顯示右顳骨蝕骨性之腫塊。病患於是接受開顱手術切除腫塊,病理切 片顯示為骨肉瘤。術後,病患接受化學治療。但是,八個月後出現局部復發,病患再次 接受開顱手術及化學治療。雖經積極治療,病患又再出現局部復發及肺部轉移。病患於 診斷 14 個月後死亡。顱骨之放射線引發骨肉瘤,乃腦瘤放射治療,罕見且預後極差之併發症。 |
英文摘要 | A 32-year-old female suffered from a bulging mass over the right temporal area 4 years after radiotherapy for intraventricular neurocytoma. Computed tomography and magnetic resonance imaging revealed an osteolytic lesion over the right temporal bone. The patient underwent a craniotomy procedure for resection of the tumor, and the histological diagnosis was osteosarcoma. Postoperative adjuvant chemotherapy was administered. However, local recurrence developed 8 months later, and the patient again underwent surgical resection and chemotherapy. Though aggressively treated, the patient deteriorated due to local recurrence and lung metastasis, and she died 14 months after the diagnosis. Ultimately, radiation-induced osteosarcoma of the skull bone is a rare complication of radiotherapy for brain tumor, with a generally poor prognosis. |
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