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| 題 名 | Recurrent Malignant Parotid Gland Tumor, Acinic Cell Carcinoma--A Case Report and Literature Review=罕見的復發性惡性腮腺腫瘤--腺泡細胞癌:病例報告及文獻討論 |
|---|---|
| 作 者 | 楊舒鈞; 陳信翰; 林智一; 許永昌; 吳肇毅; 張家寧; 陳宏基; | 書刊名 | 臺灣整形外科醫學會雜誌 |
| 卷 期 | 21:1 2012.03[民101.03] |
| 頁 次 | 頁40-47 |
| 分類號 | 416.21 |
| 關鍵詞 | 惡性腮腺腫瘤; 腺泡細胞癌; 唾液腺體腫瘤; Malignant salivary gland tumor; Parotid gland tumor; Acinic cell carcinoma; |
| 語 文 | 英文(English) |
| 中文摘要 | 背景:在頭頸部腫瘤之中,唾液腺體腫瘤相對地少見,且大多數為良性腫瘤。唾液腺腫瘤約有百分之六十五至百分之八十發生於腮腺,且約有百分之二十的機會為惡性。相較於黏液類上皮細胞癌,腺泡細胞癌實屬罕見。目的及目標:在此我們提出一例復發腺腺腺泡細胞癌的病例報告,分享我們的治療經驗及回顧有關其臨床表徵、特殊的病理特徵、與手術治療的文獻。材料及方法:一位七十一歲的婦人,於十一年前因右側腮腺腺泡細胞癌併右側顏面神經侵犯接受過右側淺葉腮腺摘除。經過了九年的時間,右耳前方再次出現一腫塊,鑑於復發惡性腫瘤,此次我們為她安排右側全腺腺摘除。另外,因為其病理報告出現較高轉移風險之特徵,此患者於術後接受放射治療。結果:病理報告證實為復發腺腺腺泡細胞癌。於術後兩年的追蹤,病人滿意手術部位的功能及外觀,且無相關併發症及復發跡象。結論:腮腺腺泡細胞癌是非常罕見的。手術切除是處理這類腫瘤的標準作法。若病理報告出現較侵略性的特徵,術後接受放射治療是可行的治療方法。通常此腫瘤的惡性程度較低且進展緩慢,所以長時間的追蹤是必要。 |
| 英文摘要 | Background:Salivary gland tumors are relatively uncommon in the head and neck neoplasms, and majority of them are benign. Most of them, about 65% to 80%, arise in the parotid gland and 20 percent of parotid gland tumors are malignant. Compared to most commonly mucoepidermoid carcinoma, acinic cell carcinoma is very rare.Aim and objectives:Herein we present a case with this rare malignant parotid gland tumor, and share our management experience. Clinical presentation, specific histopathologic characteristics, and therapeutic management of acinic cell carcinoma in the parotid gland are discussed.Materials and Methods:A 71-year-old woman had the history of right parotid gland acinic cell carcinoma with facial nerve involvement and received superficial paroidectomy eleven years ago. After a silent period, the tumor was found to recur one month before the current treatment. A total parotidectomy was performed, and an adjuvant radiation therapy was subsequently given based on the pathology report which showed high-risk features.Results:The pathology report demonstrated parotid gland acinic cell carcinoma with clear margins. After adjuvant radiation therapy and two-year follow-up, there was no sign of recurrence, and the patient was satisfied with the functional and cosmetic outcomes.Conclusion:Parotid gland acinic cell carcinoma is a very rare neoplasm. It often has low-grade potential, and surgical extirpation is the choice of treatment when managing such a case. Post-operatively adjuvant radiation therapy is practicable if the pathology has high-grade potential or high-risk features. Parotid gland acinic cell carcinoma might recur after a long period due to its indolent nature. Thus, a long-term follow-up is necessary. |
本系統中英文摘要資訊取自各篇刊載內容。