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題名 | Multinodular Goiter, Concomitant Microcarcinoma and Lymphocytic Thyroiditis Manifesting as Thyroid Autonomy=多結節性甲狀腺腫並存乳突狀癌和淋巴球性甲狀腺炎:以自主功能性結節為表徵 |
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作者姓名(中文) | 楊容欣; 胡蓮欣; 張智勇; 朱任公; | 書刊名 | 核子醫學雜誌 |
卷期 | 24:1 2011.03[民100.03] |
頁次 | 頁22-24 |
關鍵詞 | 自主功能性結節; 甲狀腺乳突狀癌; 多結節性甲狀腺腫; 淋巴球性甲狀腺炎; Autonomous functioning nodule; Multinodular goiter; Papillary thyroid carcinoma; Lymphocytic thyroiditis; |
語文 | 英文(English) |
中文摘要 | 多結節性甲狀腺腫、乳突狀癌、淋巴球性甲狀腺炎與自主功能性結節,在核醫掃描中各有不同的特徵,甲狀腺癌在核醫掃描中的表現為「冷」結節,掃描出現的「熱」結節大多數被認為良性病灶。我們報告一個獨特的案例,一名64歲婦人有亞臨床性甲狀腺機能亢進,核醫掃描看見甲狀腺「熱」結節,疑似自主功能性結節而接受甲狀腺右葉切除手術;病理學發現病灶中有多結節性甲狀腺腫、乳突狀癌和淋巴球性甲狀腺炎等多類病變同時並存。這一病例意味著上述各個病灶之間,有某些共同的致病機轉存在。 |
英文摘要 | Papillary thyroid carcinoma (PTC), multinodular goiter (MNG) and autonomous functioning nodule (AFN) have always been considered different from each other, in theft behavior and histopathological features. Generally speaking, an AFN appears "hot" and the majority of thyroid carcinomas present as a "cold" nodule on radionuclide scintigraphy. A MNG is usually thought to result from a hyperplastic response of the gland to certain stimulus, showing heterogenous tracer concentration. We report a subclinical hyperthyrotic woman, with thyroid autonomy on Tc-99m scintigraphy, who received hemithyroidectomy. The specimen histologically showed MNG concomitant microcarcinoma and lymphocytic thyroiditis. This unique composition of different thyroid lesions in the same lobe implies certain common mechanisms leading to the pathogenesis of lesions. |
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