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| 題 名 | 酒精性肝炎藥物治療趨勢=The Tendency of Drug Therapy for Alcoholic Hepatitis |
|---|---|
| 作 者 | 蘇美欣; 許明豪; | 書刊名 | 藥學雜誌 |
| 卷 期 | 27:4=109 2011.12[民100.12] |
| 頁 次 | 頁86-90 |
| 分類號 | 415.533 |
| 關鍵詞 | 酒精性肝炎; 藥物治療; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 酒精性肝炎是長期飲酒所造成的酒精性肝疾病。主要的臨床表徵為急性的黃疸、發燒、體重減輕等現象,嚴重的酒精性肝炎病人可能伴有腹水、肝腦病變;酒精性肝病在台灣並不罕見,也可能是造成肝硬化的重要原因。 從流行病學的角度來看,肝硬化的風險與酒精攝取的劑量成等比例相關。在肝硬化的病人裡,約有1%的肝硬化病人每日攝取30~60公克的酒精,更有高達5.7%的病人每日攝取超過120公克的酒精。臨床試驗中,許多藥物被探討用來治療酒精性肝炎,但試驗結果都多有意見紛歧。本文透過文獻的搜尋與整理,以醫學的角度來探討有關酒精性肝炎治療藥物的治療趨勢,希望能提供讀者系統性的了解與認識。 |
| 英文摘要 | Alcoholic hepatitis is an alcoholic liver disease caused by long-term alcohol abuse. The main clinical manifestations include acute jaundice, fever, weight loss, etc. Severe alcoholic hepatitis may be accompanied by ascites and/or encephalopathy. Alcoholic liver disease , which is not rare in Taiwan , may lead to hepatic cirrhosis. From the point of view of epidemiology, the risk of hepatic cirrhosis is proportional to alcohol consumption. Among hepatic cirrhosis patients, approximately 1% consume 30-60 gm of alcohol daily, and up to 5.7% consume more than 120 g daily. In clinical studies, many drugs have been investigated for their ability to treat alcoholic hepatitis, but results have been inconclusive, Through the study of evidence-based literature, this article seeks to provide the reader with an updated review of the epidemiology, diagnosis, and treatment of alcoholic hepatitis. |
本系統中英文摘要資訊取自各篇刊載內容。