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頁籤選單縮合
題 名 | Metastatic Extra-gonadal Germ Cell Tumor Appearing as a Neck Mass=以頸部腫塊表現的轉移性生殖細胞癌 |
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作 者 | 陳佩詩; 呂宜興; 黃志銘; 林炯森; 陳瑜珍; | 書刊名 | 臺灣癌症醫學雜誌 |
卷 期 | 26:1 2010.02[民99.02] |
頁 次 | 頁28-31 |
分類號 | 416.212 |
關鍵詞 | 頸部轉移; 絨毛膜癌; 性腺外生殖細胞瘤; Cervical metastasis; Choriocarcinoma; Extragonadal germ cell tumor; |
語 文 | 英文(English) |
中文摘要 | 性腺外絨毛膜癌好發於年輕之男性,常見的分布位置為身體中線,依機率高低為 縱膈腔、松果體區、骶尾骨區、後腹膜腔,而肺、肝、骨頭及腦部為其常見轉移部位, 轉移至頭頸部並不常見。在所有轉移至頭頸部的原發惡性腫瘤中,最常見的還是頭頸 部癌症及惡性淋巴瘤,絨毛膜癌轉移至頭頸部相當罕見,根據文獻報導只有零星幾例 病例報告。本科於2008 年12 月,經歷一位25 歲男性因近一個月來腹部疼痛至內科求診無效,安排腹部超音波發現肝門附近多處淋巴結腫大,而後轉介至血液腫瘤科行 進一步檢查,理學檢查發現左側頸部淋巴結腫大併頸部腫塊。經由本科進行頸部淋巴 結切片術後,β-HCG 相當高(H 46508.0 mIU/mL,參考值males:< 0-5 mIU/mL), AFP(399.31 ng/mL, 參考值 <6.00 ng/mL)及LDH( H 1468IU/L,參考值範圍 98-192 IU/L )確有高於血中正常濃度,確定病理報告為轉移性絨毛膜癌。陰囊超音波檢查並 無發現腫塊跡象。病患於2009 年一月至七月陸續接受九次化學治療(五次EMA/CO 療程,四次BEP 療程),現仍持續追蹤中。因為病例罕見,特提出報告。 |
英文摘要 | Extragonadal choriocarcinoma usually presents in the midline of the body, such as the anterior mediastium, pineal gland, sacrococcygeal region and retroperitonium. Extragonadal choriocarcinoma may metastasize to retroperitoneal lymph node, lungs, liver, bone and brain. Metastasis to neck mass is exceedingly rare. We report a rare case of a 25-year-old male who had neck and intra-abdominal masses as the inintial manifestation of extragonadal choriocarcinoma. The patient received five courses chemotherapy of regimen EMA/CO and four courses of BEP. The patient was found with no evidence of disease progression or development of new symptoms in during follow-up. |
本系統中英文摘要資訊取自各篇刊載內容。