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題 名 | Idiopathic Granulomatous Mastitis--A Problematic Wound in Breast--Case Report=不明原因肉芽性乳腺炎所致之困難傷口處理--病例報告 |
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作 者 | 陳柵君; 謝承翰; 林煌基; 鄭舉緒; 林育賢; 許雅芬; 周玉瑜; | 書刊名 | 臺灣整形外科醫學會雜誌 |
卷 期 | 20:3 2011.09[民100.09] |
頁 次 | 頁224-229 |
分類號 | 416.226 |
關鍵詞 | 自發性肉芽腫乳腺炎; Idiopathic granulomatous mastitis; Non-puerperal mastitis; |
語 文 | 英文(English) |
中文摘要 | 背景:自發性肉芽腫乳腺炎是一種罕見的非育乳性乳腺炎。此疾病於Kessler和Wolloch在1972年由病理發現診斷。雖然此疾病於臨床上和一般乳房膿瘍難以鑑別,但若是照一般抗生素或是手術處理常會造成難以癒合之傷口。以下藉由此案例討論此疾病之治療。目的及目標:一個35歲女性自發性肉芽腫乳腺炎之案例報告以及治療討論。材料及方法:這位女性先接受手術治療,但是因局部傷口持續潰爛,且細菌培養皆無生長,故之後用5mg口服類固醇治療。傷口則先用Bacitracin藥膏處理。結果:乳腺炎於五周口服類固醇後痊癒。十二個月內未服用口服類固醇或是抗生素亦無復發之現象。結論:自發性肉芽腫乳腺炎的治療,應以全身性免疫抑制劑如類固醇爲優先,手術清創引流反而會形成復發且難以癒合之傷口。 |
英文摘要 | Background:Idiopathic granulomatous mastitis is a rare benign inflammatory breast disease. Like the autoimmune disease, pyoderma gangrenosum, surgical debridement may lead to problematic wound healing unless aggressive mastectomy is performed. However, some immune-suppressive agents may help wound healing.Aim and Objectives:Treatment of idiopathic granulomatous mastitis by both surgical and medical strategies was discussed.Materials and Methods:A 35 year-old female was diagnosed of idiopathic granulomatous mastitis through pathological examination. Excision biopsy was done but inadequate wound healing with local ulceration was observed. Therefore, oral 5mg prednisolone was prescribed for anti-inflammatory therapy.Results:His wound healed appropriately 3 weeks after oral prednisolone. No recurrent episodes were noted during the follow-up period of 12 months.Conclusion:Oral immune-suppressive agents, instead of surgery, may be the first line therapy of idiopathic granulomatous mastitis when breast preservation is concerned. This therapeutic strategy should be provided to the patients with IGM by both plastic and general surgeons. |
本系統中英文摘要資訊取自各篇刊載內容。