頁籤選單縮合
題名 | 避免顯影劑引起腎病變之建議=Recommendation for Prevention of Contrast Medium Induced Nephropathy |
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作者 | 楊雅萍; 王芙容; 戴慶玲; | 書刊名 | 藥學雜誌 |
卷期 | 27:2=107 2011.06[民100.06] |
頁次 | 頁144-148 |
分類號 | 418.346 |
關鍵詞 | 顯影劑腎病變; 心血管處置; Contrast-induced nephropathy; Cardiovascular angiographic procedures; CIN; |
語文 | 中文(Chinese) |
中文摘要 | 心血管攝影發生顯影劑腎病變 (CIN)的機率約 2-30%,常會顯著增加病患的罹病率及死亡率。先評估哪些病患是 CIN的高危險群,並在心導管處置前中後給予適當的預防與處置,可明顯降低 CIN的發生率。由於慢性腎臟病是主要造成 CIN的因素,所以將腎絲球過濾率 (GFR)小於 60毫升 /分鐘的腎功能不全患者定義為 CIN的高危險群。在 CIN高風險的病人,建議先暫停腎毒性藥物的使用、給予靜脈輸液補充、高劑量的 N-acetylcysteine、使用較低劑量的顯影劑及選擇低張或等張滲透壓的顯影劑來降低 CIN的發生率。 |
英文摘要 | The risk of contrast-induced nephropathy (CIN) varies from 2-30% in unselected patients undergoing cardiovascular angiographic procedures. It is associated with a significant increase in patient morbidity and mortality. Recognition of the high risk patient coupled with appropriate peri-, intra-and post-procedural management can reduce the incidence of CIN. As chronic kidney disease is the primary predisposing factor for CIN, the glomerular filtration rate below 60 mL/min is used to define the patient at high risk for developing CIN. In the patient at increased risk for CIN, it is appropriate to withhold potentially nephrotoxic medications, consider adequate parenteral volume repletion, use high dose N-acetylcysteine, limit contrast volume and use low-or iso-osmolar contrast medium to decrease the incidence of CIN. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。