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題 名 | 自體免疫性肝炎之藥物治療=The Pharmacotherapy for Autoimmune Hepatitis |
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作 者 | 洪照輝; 李榮明; 陳怡莉; | 書刊名 | 藥學雜誌 |
卷 期 | 27:2=107 2011.06[民100.06] |
頁 次 | 頁79-84 |
分類號 | 418.29 |
關鍵詞 | 自體免疫性肝炎; 自體抗體; 免疫抑制療法; 肝臟首渡效應; Autoimmune hepatitis; First-pass effect; |
語 文 | 中文(Chinese) |
中文摘要 | 自體免疫性肝炎是一種自發性的肝臟疾病,它的特徵是為肝臟處於慢性發炎狀態,且血液循環中伴隨著自體抗體及高濃度的伽馬球蛋白。這個疾病可發生在各年齡層的所有種族中,雖然醫藥科技對許多慢性肝炎疾病的治療有很大的提升,但自體免疫性肝炎的治療方式過去的五十年來仍未曾有所進展,其一般對免疫抑制療法具有不錯的反應性,也是一個經藥物治療能夠提升存活率的慢性肝病。若因為藥物治療皆失效時,唯有肝臟移植是較適切的處理方式。 |
英文摘要 | Autoimmune hepatitis (AIH) is an idiopathic hepatitis characterized by inflammation of the liver, presence of auto-antibodies, and evidence of increased gamma globulins in the serum. This disease is seen in all ethnic groups and at all ages. Although medical science has made significant advances in the treatment of many chronic liver diseases, our treatment of AIH is essentially unchanged over the last 50 years. AIH is generally responsive to immunosuppressive treatment and it was the first chronic liver disease in which medical therapy improved survival. The ultimate treatment approach upon drug treatment failure is liver transplantation. |
本系統中英文摘要資訊取自各篇刊載內容。