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頁籤選單縮合
題名 | Higher Percentage of Stage 1 Sleep Predicts Excessive Daytime Sleepiness in Middle-Aged Obstructive Sleep Apnea Males=高比例之第一期睡眠是中年男性阻塞性睡眠呼吸中止症患者白天嗜睡之預測因子 |
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作者姓名(中文) | 周育廷; 林裕清; 林進國; 張家豪; 楊政達; 蔡熒煌; 張薷方; 楊聰明; | 書刊名 | 胸腔醫學 |
卷期 | 26:4 2011.08[民100.08] |
頁次 | 頁179-186 |
分類號 | 415.472 |
關鍵詞 | 過度嗜睡; 阻塞性睡眠呼吸中止症; 多頻道睡眠檢查; 睡眠分期; Hypersomnia; Obstructive sleep apnea; Polysomnography; Sleep stages; |
語文 | 英文(English) |
中文摘要 | 背景:造成阻塞性睡眠呼吸中止症病患白天過度嗜睡的主要原因目前仍未定論。在我們的研究中,我們發現高比例之第一期睡眠是中年男性阻塞性睡眠呼吸中止症患者白天嗜睡之預測因子。方法:我們收集2005年9月至2007年8月嘉義長庚紀念醫院中年男性阻塞性睡眠呼吸中止症病患之多頻道睡眠檢查報告。一共有50位病人的資料符合收入條件,其中Epworth睏睡度量表(Epworth sleepinesss cale, ESS)分數等於或大於20分之患者被分為白天過度嗜睡(EDS)組,而ESS分數小於4的患者則被分為非白天過度嗜睡(Non-EDS)組,我們比較者兩組睡眠檢查結果之差異,以找出中年男性阻塞性睡眠呼吸中止症患者是否會有白天過度嗜睡之預測因子。結果:將EDS組與Non-EDS組做比較,我們發現EDS組有較高的呼吸性覺醒指數(respiratory arousal index)以及總覺醒指數(total arousal index),較高比例的第一期睡眠(stage 1 sleep)、較低比例的第二期睡眠(stage 2 sleep),以及較低比例的慢波期睡眠(slow wave sleep)。經由邏輯回歸分析(logistic regression)結果,我們發現高比例的stage 1 sleep是決定病患是否會有白天過度嗜睡的唯一獨立預測因子(OR=1.052, 95% confidence interval=1.011-1.096; p=0.013)。結論:高比例的 stage 1 sleep是中年男性阻塞性睡眠呼吸中止症病患是否會有白天過度嗜睡的主要決定因子。 |
英文摘要 | Introduction: The etiologies of excessive daytime sleepiness (EDS) in obstructive sleep apnea (OSA) remain uncertain. We found that the percentage of stage 1 sleep is an important predictor of excessive daytime sleepiness (EDS) in middle-aged OSA males.Materials and Methods: We retrospectively reviewed the polysomnography (PSG) results of 363 middle-aged OSA patients. A total of 50 patients were enrolled in the final analyses. Patients with an Epworth Sleepiness Scale (ESS) score equal to or more than 20 comprised the EDS group. Patients with an ESS score equal to or less than 4 were included in the non-EDS group. We compared the PSG results between these 2 groups of patients to survey for possible predictors of EDS in middle-aged OSA males.Results: Patients in the EDS group had a higher respiratory arousal index, total arousal index, and percentage of stage 1 sleep. In addition, both the stage 2 sleep and slow wave sleep percentages were lower in the EDS group, compared with that in the non-EDS group. Logistic regression analysis showed that a higher percentage of stage 1 sleep is an independent predictor of EDS in middle-aged OSA males.Conclusions: A higher percentage of stage 1 sleep is an important predictor of EDS in middle-aged OSA males. |
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