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相關文獻
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頁籤選單縮合
題名 | Risperidone-induced Leukopenia and Neutropenia=Risperidone引起之低白血球症及低嗜中性球症 |
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作 者 | 洪誌遠; 白雅美; | 書刊名 | Taiwanese Journal of Psychiatry |
卷期 | 25:2 2011.06[民100.06] |
頁次 | 頁119-122+128 |
分類號 | 418.21 |
關鍵詞 | 理思必妥; 低白血球症; 低嗜中性球症; Risperidone; Leucopenia; Neutropenia; Blood dyscrasias; |
語文 | 英文(English) |
英文摘要 | Background: Risperidone tends to have a lower risk of hematotoxicity. Here, we report a woman patient who developed risperidone-induced neutropenia. Case Report: A 64-year-old female patient with a diagnosis of bipolar disorder had received several antipsychotics previously, without a history of neutropenia or leucopenia. During a depressive episode with psychotic feature, she received risperidone 3.5 mg/day, lamotrigine 100 mg/day, and valproic acid 1,000 mg/day. Four weeks later, she had leukopenia (white blood cells [WBC]: 2900/mm^3) and neutropenia (1,131/mm^3) were noted in the regular laboratory test. Initially we suspected the lamotrigine was related to the neutropenia and discontinued it, and increased risperidone to 5 mg/day. Five days later, the neutrophil was further decreased to 1,015/mm^3, so we discontinued risperidone and switched risperidone to 5 mg/day to sulpiride 600 mg/day. Twelve days later, the WBC and differential count were returned to normal limits. Conclusion: This is the first report of risperidone-induced leukopenia and neutropenia in Taiwan. |
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