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題 名 | Intravenous Ondansetron as Antiemetic Prophylaxis for Postoperative Nausea and Vomiting after Shoulder Arthroscopy=骨科肩關節鏡手術結束前常規靜脈注射卓弗蘭(Ondansetron)對於降低術後噁心嘔吐發生率的效果研究 |
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作 者 | 陳怡帆; 葉文凌; 李科宏; 李銘杰; 楊宗憲; 黃新家; 黃宗斌; 何欣怡; | 書刊名 | 長庚醫誌 |
卷 期 | 34:2 2011.03-04[民100.03-04] |
頁 次 | 頁205-212 |
分類號 | 418.243 |
關鍵詞 | 術後噁心嘔吐; 肩關節鏡; 卓弗蘭; 預防噁心嘔吐; Postoperative nausea and vomiting; PONV; Shoulder arthroscopy; Ondansetron; Prophylactic antiemetics; |
語 文 | 英文(English) |
英文摘要 | Background: Nausea and vomiting are common chief postoperative complaints. The clinical literature indicates that postoperative nausea and vomiting (PONV) is common after orthopedic surgery. This study examines the clinical therapeutic efficacy of Ondansetron injected intravenously before the end of shoulder arthroscopy as antiemetic prophylaxis to help reduce the incidence of PONV. Methods: Participants were identified through retrospective chart review and patients undergoing shoulder arthroscopy performed by the same orthopedic surgeon at the same hospital from 2005 to 2009 were analyzed. Subjects were classified into two groups based on whether Ondansetron was given. Differences in the incidence of PONV among the two groups were compared. Basic patient information, anesthesia records, and surgical records were obtained, as well as records on PONV, postoperative pain intensity, and postoperative analgesic injections within 24 hours after surgery. Results: The study involved 90 patients. The Group A contained 34 patients who did not receive Ondansetron, and the Group B contained 56 patients who were given Ondansetron. Analytical results for the postoperative 24 hour period showed a significant difference in the incidence of vomiting between the two groups, with a lower incidence (p < 0.05) for the. Group B. However there was no significant difference in the incidence of nausea between the two groups in the same postoperative 24 hour period, although there was a trend of a lower incidence in the Group B (p = 0.17). The overall incidence of PONV during the 24-hour period was lower in the Group B (14%) than the Group A (32%), and the Group B demonstrated lower pain intensity and lower analgesic injection needs. Conclusion: Routine intravenous injection of Ondansetron 30 minutes before completion of shoulder arthroscopy can reduce the incidence of vomiting and overall PONV in patients. Additionally, the patients using Ondansetron demonstrated lower pain intensity and lower analgesic injection needs than the control group. |
本系統中英文摘要資訊取自各篇刊載內容。