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題 名 | 安慰劑於臨床護理研究之考量及運用=Consideration and Application of Placebo in Clinical Nursing Research |
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作 者 | 鍾玉珠; 陳靜修; 蕭冰如; 葉美玲; | 書刊名 | 志為護理 |
卷 期 | 10:3 2011.06[民100.06] |
頁 次 | 頁66-72 |
分類號 | 419.7 |
關鍵詞 | 安慰劑; 安慰劑作用; 倫理; 方法學; 護理研究; Ethics; Methodology; Nursing research; Placebo; Placebo effect; |
語 文 | 中文(Chinese) |
中文摘要 | 近年來研究之安慰劑議題已逐漸受到重視。基礎科學家開始從神經生理及心理學的過 程去解釋安慰劑反應的調節過程。安慰劑作用受疾病變異的影響,例如疾病自然過程, 而病人或醫師的偏誤也會造成對安慰劑作用的錯誤解釋。為了透過安慰劑控制組試驗移 除安慰劑作用,安慰組合併雙盲隨機之實驗設計,儼然成為現代臨床試驗之黃金準則。 因此,本文將探討安慰劑、安慰劑作用、安慰劑機轉、倫理與方法學等議題,以作為護 理介入措施研究之設計參考。 |
英文摘要 | In recent years, placebo becomes an important issue in evidence-based research. Basic sciences started elucidating the neurobiological and psychological processes that mediate the placebo response. A placebo effect is affected by the variation of illness, such as the natural course of disease. Patient or physician bias can also cause misinterpretation of the placebo effect. In research, the placebo effect is therapeutic noise to be removed by placebocontrolled trials. Thus, a randomized, double-blind, placebo-controlled trial has emerged as the gold standard in modern clinical study. The purpose of this article was to discuss the issue related to placebo, placebo effects, placebo mechanism, ethics of using placebos, and methodology referring to intervention research design of the clinical research in nursing. |
本系統中英文摘要資訊取自各篇刊載內容。