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題 名 | Cronkhite-Canada Syndrome: Report of a Case=Cronkhite-Canada症候群:一病例報告 |
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作 者 | 陳建宏; 邱逸群; 周業彬; 郭仲謀; 吳耿良; 蔡成枝; | 書刊名 | 臺灣消化醫學雜誌 |
卷 期 | 28:1 2011.03[民100.03] |
頁 次 | 頁57-61 |
分類號 | 415.5 |
關鍵詞 | Cronkhite-Canada症候群; Cronkhite-Canada syndrome; |
語 文 | 英文(English) |
中文摘要 | Cronkhite-Canada症候群是一種罕見非遺傳性的疾病。此疾病的特徵是瀰漫性胃腸息肉伴隨毛髮的改變、指甲營養不良和皮膚色素的沈積。我們報告一位74歲男性病患表現有3個月的稀糞便。此外病患這3個月內體重減輕8公斤且伴隨嚴重的食慾不振、噁心感、疲累感和偶爾會腹痛。食道胃十二指腸內視鏡顯示從胃體部中間至胃竇部分有瀰漫性小的胃息肉合併胃黏膜水腫。而食道和胃體部上半部份的黏膜是正常。大腸鏡則顯示整個大腸和直腸部分都有很多紅色的息肉。大腸息肉的切片報告顯示息肉的大腸黏膜有局部擴大增生的腺體和lamina propria有水腫和發炎細胞的浸潤。基於典型的臨床表現和息肉組織學的 |
英文摘要 | Cronkhite-Canada syndrome (CCS) is a rare nonhereditary disorder characterized by the presence of diffuse gastrointestinal polyposis associated with hair alterations, nail dystrophy and skin pigmentation. We reported a 74-year-old man who presented with loose stool for 3 months. In addition, he had a 3-month history of weight loss (about 8 kg) and associated with severe anorexia, nausea sensation, fatigue, and occasional abdominal pain. The patient appeared alopecia, fingernail dystrophy and hyperpigmentation of sun-exposed skin over the palms, extremities, face, soles and neck. Esophaogastroduodenoscopy revealed diffuse small polypoid lesions with mucosa edema within the stomach from mid-body to antrum. Both the esophagus and upper stomach mucosa were normal. A colonoscopy was performed subsequently, showing numerous, red polyps throughout the colon and rectum. Biopsy specimen taken from colon displayed polypoid colonic mucosa composed of hyperplastic glands with focal dilatation and inflammatory cell infiltration in edematous lamina propria. Based on typical clinical features and histological findings of polyps, a diagnosis of CCS was made. Patient did not receive treatment in our hospital because he lost to follow after the diagnosis of CCS. |
本系統中英文摘要資訊取自各篇刊載內容。