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題 名 | 疑似Herpes Zoster Virus引起多形性紅斑之個案報告=Suspected Herpes Zoster Virus Inducing Erythema Multiforme--A Case Report |
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作 者 | 張麗雯; 朱婉兒; 李桂花; 陳立奇; 許秀蘊; | 書刊名 | 藥學雜誌 |
卷 期 | 26:4=105 2010.12[民99.12] |
頁 次 | 頁131-138 |
分類號 | 417.5643 |
關鍵詞 | 多形性紅斑; 帶狀疱疹; Stevens-johnson syndrome; Naranjo scale; Adverse drug reaction; |
語 文 | 中文(Chinese) |
中文摘要 | 多形性紅斑的臨床表現複雜,必須尋找病因(可能是藥物、病毒或細菌引起)。本案例疑似 rifampicin、famotidine引起的 Stevens-Johnson syndrome,經 Naranjo scale評量藥物不良反應( adverse drug reaction; ADR),並參考病人的血液生化值、病史、有無過去發生案例等,復經縝密的臨床診斷與理學檢查,最後確認是由感染水痘 -帶狀疱疹病毒引起的多形性紅斑。帶狀疱疹發疹的 72小時內投予抗病毒藥物,可以縮短發疹的時間,減緩病程擴展及帶狀疱疹後神經性疼痛。 |
英文摘要 | Accurate identification of the pathogenic sources is essential for efficient treatment of erythema multiforme. We reported a strategy that successfully identified the Stevens-Johnson syndrome that was originally diagnosed and suggested to be induced by rifampicin and famotidine. The study involving a combination of adverse drug reactions evaluated with Naranjo scale, the biochemical data, and medical history before herpes zoster virus verified and concluded as the source that causing the erythema multiforme. It was further found that treating with antiviral drugs within seventy-two hours after the onset of clinical manifestation of erythema multiforme significantly reduced the disease progression and it relieved the post-herpetic neuralgia. |
本系統中英文摘要資訊取自各篇刊載內容。