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題名 | 使用肉毒桿菌素注射治療頸部蛤蟆腫--病例報告=Treatment of Plunging Ranula with Botulinum Toxin Injection--A Case Report |
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作者 | 陳孟延; 王東堯; 黃振勳; 陳畊仲; | 書刊名 | 臺灣口腔顎面外科學會雜誌 |
卷期 | 22:2 2011.06[民100.06] |
頁次 | 頁139-149 |
分類號 | 416.89 |
關鍵詞 | 蛤蟆腫; 肉毒桿菌素; 口腔癌; 術後併發症; Plunging ranula; Botulinum toxin; Oral cancer; Post-operation complication; |
語文 | 中文(Chinese) |
中文摘要 | 唾液囊腫的定義爲唾液腺的唾液溢出管腔並形成一無上皮之假性囊腫。唾液囊腫如出現在舌腹之下,常爲一無痛或許帶有腫脹感之半透明腫塊。像青蛙的氣囊而得名蛤蟆腫,其治療方法不外乎冷凍療法、雷射切除,視情況合併造袋術或外科手術切除相關的唾液腺;上述的方法皆具侵略性,並有病灶再發或傷害到週遭器官的可能性。我們提出一位50歲男性病例,因舌部惡性腫瘤切除造成舌下腺缺損,術後四個月,口底發現有一無痛且具波動感之腫塊,由臨床發現與電腦斷層檢查診斷爲頸部蛤蟆腫。我們施予兩次共九十單位的肉毒桿菌素於右側舌下腺,蛤蟆腫情況漸改善並經過三年的回診追蹤並與任何復發跡象。我們提出此一利用肉毒桿菌素作爲醫源性頸部蛤蟆腫治療方法的病例,並討論肉毒稈菌素對唾液腺抑制的可能機制。 |
英文摘要 | Sialocele is extravasation of saliva from salivary gland or duct, and gives rise to a pseudocyst lacking an epithelial lining. There are several ways to treat ranula, including cryosurgery, laser evaporation, marsupialization and surgical excision. These procedures are more or less invasive or having high recurrence rate. We presented a case report in which a fifty-year-old male who received tongue cancer operation developed post-operative plunging ranula. He had undergone tumor wide excision and upper neck dissection in June, 2006. Four months after operation, there was a painless, and fluctuated mass over right mouth floor. Aspiration showed clear, and yellowish sticky fluid. Computer tomography study showed fluid accumulation across mylohyoid muscle. Plunging ranula was diagnosed. A total of ninety units of type A Botulinum toxin was injected into right sublingual gland divided into two dose. The plunging ranula disappeared ten months after first injection. There was no evidence of tumor or ranula recurrence within three years follow up. |
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