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題名 | Atrial Size Independently Correlates with the Development of Paroxysmal Atrial Fibrillation in Patients with Sick Sinus Syndrome=心房大小的變化在病竇症候群病人中是否發展成心房顫動有獨立的相關性 |
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作者 | 林祐賸; 郭必芳; 陳永隆; 蔡子賢; 潘國利; 劉文浩; 陳建仁; 楊正旭; 方志元; 謝元凱; 陳勉成; | 書刊名 | 長庚醫誌 |
卷期 | 33:6 2010.11-12[民99.11-12] |
頁次 | 頁659-667 |
分類號 | 415.318 |
關鍵詞 | 心房顫動; 心房大小; 病竇症候群; Atrial fibrillation; Atrial size; Sick sinus syndrome; |
語文 | 英文(English) |
英文摘要 | Background : Atrial fibrillation arises in 20-30% of patients with sick sinus syndrome, increasing the risk of systemic embolization and mortality. The aim of this study was to examine the clinical determinants of development of paroxysmal atrial fibrillation in sick sinus syndrome patients before implantation of a pacemaker. Methods : This case-control survey involved 144 patients (mean age SD age: 72 9 years) in whom implantation of a transvenous permanent pacemaker was planned for sick sinus syndrome. Patients were classified into two groups, patients with (n = 71) and without (n = 73) a history of paroxysmal atrial fibrillation before implantation. Clinical characteristics and echocardiographic parameters were analyzed. Results : The peri-implant right atrial area and left atrial area were significantly larger in patients with, than those without, paroxysmal atrial fibrillation. Multiple logistic regression analysis identified that the size of the left atrial area independently correlated with the development of atrial fibrillation: each 1 cm2 increase in left atrial area corresponded to a 44% increase in risk (odds ratio = 1.44 [1.22, 1.71]; p < 0.001). Conclusions : The left atrial size independently correlates with the development of paroxysmal atrial fibrillation in sick sinus syndrome patients before pacemaker implantation. |
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