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頁籤選單縮合
題名 | Clinical Features and Outcome Analysis of Patients Suffer from Paraquat Intoxication in Central Taiwan=中臺灣地區巴拉刈中毒的臨床特徵及相關預後分析 |
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作者姓名(中文) | 林秀敏; 劉信良; 楊美雀; 蔡宗憲; 周志中; 張進富; 陳惠敏; 林晏任; | 書刊名 | 臺灣急診醫學會醫誌 |
卷期 | 12:4 2010.12[民99.12] |
頁次 | 頁99-106 |
分類號 | 418.733 |
關鍵詞 | 巴拉刈中毒; 預測因子; 有機磷; 職業; 存活; Paraquat intoxication; Predictors; Organophosphate; Occupation; Survival; |
語文 | 英文(English) |
英文摘要 | Objective: The outcome of paraquat intoxication is well known to be poor. The purpose of this study is to identify the patient clinical features and the predictors of patient survival among individuals with paraquat intoxication from central Taiwan. Methods: This retrospective study is comprised of 103 patients who suffered from paraquat intoxication and presented at the emergency department of a medical center between January 2004 and December 2009. The demographics, clinical features and outcomes of these patients are presented. The variables that lead to survival vs. non-survival are also analyzed. Furthermore, the factors associated with the median duration of hospitalization among the patients who survived to discharge are investigated. Finally, the prevalence of different categories of pesticides in central Taiwan is reviewed. Results: In patients with oral route intoxication (n=101), the survivors were significantly younger than those who were non-survivors (p<0.001). In addition, the amount of paraquat ingested by the survivors was less than that of the non-survivors (p=0.001). Most patients were unemployed (52.5%) and their outcome was poorer than for other occupations (p=0.02). The median duration of hospitalization was significantly longer in patients who had attempted suicide than those poisoned accidentally (p=0.029), who had higher values of paraquat detected in their urine (p=0.029) and who had acute lung injury (p=0.005). Among the 70 non-survivors, those that received hemoperfusion survived longer. Finally, in terms of pesticides intoxication in central Taiwan, paraquat and organophosphate poisoning are the leading causes. Conclusion: The demographics and predictors of outcome among patients with paraquat intoxication are presented. The duration of hospitalization was dependent on the level of paraquat detected in urine. Most importantly, an older age, the amount of paraquat ingested, being unemployed and intentional poisoning were key factors contributing to a poor prognosis. |
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