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頁籤選單縮合
| 題 名 | Immunosuppressive Therapy in Chronic Hepatitis B Induced Fulminant Hepatic Failure |
|---|---|
| 作 者 | 謝坤屏; 黃意文; 許筌淵; 蔡斌智; | 書刊名 | 藥學雜誌 |
| 卷 期 | 26:3=104 2010.09[民99.09] |
| 頁 次 | 頁3-9 |
| 分類號 | 418.29 |
| 關鍵詞 | 免疫抑制劑; 風濕性關節炎; B型肝炎; Immunosuppression; Hepatitis B; Hepatitis flare; Methotrexate; |
| 語 文 | 英文(English) |
| 中文摘要 | 猛爆性肝炎發作與 B型肝炎病毒被活化相關,在發病時可能伴隨無症狀或有症狀發生,最終可能導致肝臟代償不全及死亡。 本病例報告為 69歲婦人患有風濕性關節炎並且以免疫抑制劑( methotrexate and methylprednisolone)進行治療,最終由於引起 B型肝炎病毒被活化而導致病患猛爆性肝衰竭。 藉由此案例報告指出風濕性關節炎病患且為 B肝帶原在給予免疫抑制劑治療前須進行一些重要的檢查,例如 HBsAg, anti-HBc及/或Hepatitis B virus DNA,以及在給予免疫抑制劑治療之前建議先投予預防性抗病毒藥物來預防猛爆性肝炎的發生。 |
| 英文摘要 | Hepatitis B flares are associated with hepatitis B virus reactivation, which may be asymptomatic or symptomatic, and may result in rapid hepatic decompensation and death. The case was a 69-year-old female with rheumatoid arthritis using immunosuppressive therapies (methotrexate and methylprednisolone), finally suffered from fulminant hepatic failure due to hepatitis B virus flare-up. The case report indicates that examinations, such as HBsAg, anti-HBc and/or hepatitis B virus DNA, and prophylactic antiviral therapy are important for rheumatoid arthritis patients with hepatitis B carriers before immunosuppressive therapy. |
本系統中英文摘要資訊取自各篇刊載內容。