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題 名 | A Rare Case of Orbital Rosai-Dorfman Disease with Intracranial Extension=眼窩Rosai-Dorfman Disease 併顱內延伸--罕見病例 |
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作 者 | 許佩芬; 宋穗佳; 林祐詩; 吳建良; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷 期 | 49:2 2010.06[民99.06] |
頁 次 | 頁223-227 |
分類號 | 416.75 |
關鍵詞 | 視力模糊; 眼窩Rosai-dorfman disease併顱內延伸; 眼窩腫瘤; 鼻竇內視鏡; Orbit; Rosai-dorfman disease; S-100; Emperipolesis; |
語 文 | 英文(English) |
中文摘要 | 目的:報告一罕見之眼窩Rosai-Dorfman Disease併顱內延伸其臨床表現,組織學特徵及治療面變。方法:病例報告。結果:一名13歲男孩在半年內遭受到反覆性左眼視力模糊,經腦部核磁共振發現左眼窩頂端有一腫瘤且併顱內延伸,在接受鼻竇內視鏡切片檢查其病理組織學特徵符合Rosai-Dorfman disease;在接受化療追蹤六個月後其視力狀況穩定。結論:眼窩Rosai-Dorfman Diseas是一罕見會明顯造成視力受損的疾病。眼科醫師在發現眼窩腫瘤時要將其列入鑑別診斷之一,因其病例數不多目前治療長期預後不明。 |
英文摘要 | Purpose: We report a case of orbital Rosai-Dorfman disease with intracranial extension. The clinical presentation, histopathologic characteristics and treatment of this case will be demonstrated. Method: Case report. Result: A 13-year-old boy presented with recurrent episodes of blurred vision over his left eye. Magnetic resonance imaging examination showed left facial and skull based tumor with left orbital apex and intracranial extension. Sinus endoscopic biopsy of the lesion revealed histopathologic features of Rosai-Dorfman disease. After he underwent chemotherapy, his ocular conditions improved in the six-month follow-up period. Conclusion: Rosai-Dorfman disease is a rare and idiopathic disorder which may cause significant morbidity and even mortality. The ophthalmological manifestations of Rosai-Dorfman disease typically occur in the orbit and ocular adnexa. It is important to consider Rosai-Dorfman disease as a different diagnosis in a patient with orbital and ocular adnexal masses. The initial clinical presentation of this disease may not be pathognomonic. Prognosis for this disease still remains unclear. |
本系統中英文摘要資訊取自各篇刊載內容。