頁籤選單縮合
題 名 | 臺灣民眾肥胖與逆流性食道炎之相關性研究=The Relationship between Obesity and Reflux Esophagitis in a Taiwanese Population |
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作 者 | 賴麗容; 吳晉祥; 楊宜青; 黃盈翔; 王如雪; 盧豐華; 張智仁; | 書刊名 | 臺灣家庭醫學雜誌 |
卷 期 | 19:3 2009.09[民98.09] |
頁 次 | 頁133-143 |
分類號 | 415.516 |
關鍵詞 | 肥胖; 逆流性食道炎; 胃食道逆流; Reflux esophagitis; Central obesity; General obesity; Associated factor; Taiwanese population; |
語 文 | 中文(Chinese) |
英文摘要 | Purpose: Few studies have examined the relationship between central obesity and reflux esophagitis. The aim of this study was to investigate this relationship in a Taiwanese population. Methods: In all, 5,567 subjects (males 3,232, females 2,335, respectively; mean age, 52.2±12.7 years) received health check-ups and pan-endoscopic examinations from July 1997 to October 2007 at our medical center. Each subject completed a structured questionnaire, and body height, body weight, and waist circumference were measured by well-trained nurses. General obesity was defined according to WHO Asian-Pacific criteria, and central obesity was defined as waist circumference of 90 centimeters or more in males and 80 centimeters or more in females. Reflux esophagitis was diagnosed endoscopically and its severity was graded according to the Los Angeles classification. Results: The prevalence of reflux esophagitis was 19.5%. There were more male subjects than female subjects with reflux esophagitis (24.7% vs. 12.3%, p<0.001). A higher percentage of male subjects with reflux esophagitis than male subjects without reflux esophagitis were younger, taller, and heavier, and had a hiatal hernia, habits of tobacco smoking, alcohol drinking, and betel nut chewing, and greater body mass index, waist and hip circumference, and central obesity. A higher percentage of female subjects with reflux esophagitis than female subjects without reflux esophagitis had a hiatal hernia, and higher body weight, body mass index, and waist and hip circumference. Multiple logistic regression showed that hiatal hernia (odds ratio: 17.823), and general obesity (odds ratio: 1.328) were independently associated with reflux esophagitis in males, and only hiatal hernia (odds ratio: 56.633) was independently associated with reflux esophagitis in females. However, age, smoking, alcohol drinking, betel nut chewing, and tea drinking habits were not independently related to reflux esophagitis after adjusting for other variables. Conclusion: General obesity, male gender, and hiatal hernia are independently related to reflux esophagitis. Body mass index (BMI) of patients with reflux esophagitis should be routinely measured and reduction in BMI, not just body weight, should be recommended. |
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