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題 名 | 雙磷酸鹽類相關性的顎骨壞死--病例報告=Bisphosphonate-related Osteonecrosis (BRON) of the Jaw: Case Report |
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作 者 | 林益弘; 蔡國陽; 翁惠安; 許仁信; 盧俊泰; | 書刊名 | 臺灣牙周病醫學會雜誌 |
卷 期 | 13:3 2008.09[民97.09] |
頁 次 | 頁231-238 |
分類號 | 416.95 |
關鍵詞 | 雙磷酸鹽藥物; 骨壞死; 顎骨; Bisphosphonate; Osteonecrosis; Jaw bone; |
語 文 | 中文(Chinese) |
中文摘要 | Bisphosphonate爲雙磷酸鹽藥物,在近年來廣泛地被使用在治療骨質疏鬆與急性腫瘤骨轉移,愈來愈多的研咒報告與臨床病例指出,使用這類藥物的一個很嚴重的副作用是會導玫顎骨的骨壞死(osteonecrosis)。本文提出的病例在長期服用治療骨質疏鬆的處方用藥之一Fosamax(福善美)之後,因而引起顎骨壞死的現象。希望籍由此類的病例報告,提醒臨床醫師勿忽略了長期服用骨質疏鬆藥物的病人,以避免患者接受牙科侵襲性治療後產生顎骨壞死的情形。 |
英文摘要 | Recently, bisphosphonate was used broadly for osteoporosis and in the treatment of solid tumors with bony metastasis. More and more researches and clinical cases indicated that one of the side effects of using this kind of drugs is osteonecrosis of the jaw. Fosamax, one kind of osteoporosis drugs, chronically caused osteonecrosis of the jaw after dental treatment in our cases. These cases suggested that patients under long-term bisphosphonate use should be treated with caution. Then, osteonecrosis of jaw bone after invasive dental treatment should be avoided. |
本系統中英文摘要資訊取自各篇刊載內容。