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頁籤選單縮合
題名 | Generalized Erythematous Maculopapules with Purpuric Center in a 29-year-old Woman with Acute Myeloid Leukemia=一位29歲罹患急性骨髓性白血病的女性全身出現紅色及紫斑狀的小斑及丘疹 |
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作者 | 楊智雅; 沈瑞隆; 閻忠揚; 陳怡如; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 27:1 2009.03[民98.03] |
頁次 | 頁72-73 |
分類號 | 415.73 |
關鍵詞 | 白血病; 皮膚; 丘疹; |
語文 | 英文(English) |
英文摘要 | A 29-year-old woman with acute myeloid leukemia developed pancytopenia and fever 10 days after a second course of consolidation chemotherapy with cytarabine and idarubicin. Her full blood count revealed white cell count: 80/uL (normal 4500-10000), hemoglobin: 9.1 g/dl (normal 11.3-15.3), and platelet count: 2000/uL (normal 150000-400000). Piperacillin/tazcobactum and amikacin sulfate were prescribed, yet fever persisted. One week after fever began, generalized skin rashes and myalgia developed. Skin examination revealed multiple erythematous 3-5 mm maculopapules with purpuric center over face, trunk and limbs without symptoms (Fig. 1). An incisional biopsy was taken from the abdomen and the specimen was sent for routine H&E stain and periodic acid-Schiff stain (Fig. 2). Three sets of previously collected blood cultures grew Candida tropicalis. Antifungal agents with 50mg intravenous caspofungin acetate was administered daily and oral voriconazole 200mg was taken twice daily. Five days after treatment, fever, skin rash and myalgia had subsided. The patient was discharged in a stable condition 2 weeks later. |
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