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頁籤選單縮合
題 名 | Male Breast Cancer: Single Medical Center Experience=男性乳癌:單一醫學中心之經驗 |
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作 者 | 吳世重; 沈陳石銘; 楊景翔; 劉約維; 陳耀森; 王植熙; 楊志權; 謝崐州; 王世和; 周逢復; | 書刊名 | 臺灣外科醫學會雜誌 |
卷 期 | 40:5 2007.09-10[民96.09-10] |
頁 次 | 頁187-192 |
分類號 | 416.226 |
關鍵詞 | 男性; 乳癌; Male; Breast cancer; |
語 文 | 英文(English) |
中文摘要 | 男性乳癌不常見,它和女性乳癌有許多相似處,但也有某些差異存在。這份研究主要目的:(1)探究高雄長庚醫院過去15年來有關男性乳癌之經驗;(2)回顧有關男性乳癌之相關文獻。我們回顧性地分析高雄長庚醫院自1992年至2006年有關男性乳癌之病歷記載,詳細收載有關病人資料、癌症特性、組織病理診斷、所接受之治療以及治療成果。總共24位男性乳癌病人平均年紀是62.4歲,其中10位病人同時合併有內科方面疾病。19位病人腫瘤大小超過2公分。絕大部份組織病理診斷是侵襲性乳管上皮癌,在19位檢測病人中有15位病人(78.9%)為荷爾蒙接受器陽性。所有病人均接受改良式根治性全乳切除術,其中10位病人還接受了全乳切除術後之放射線治療。18位病人接受輔助性全身性治療,其存活率是81.3%,優於未接受輔助性全身性治療病人之存活率(40%)。在平均追蹤時間53.6個月情形下,乳癌特定存活率是71.4%,總存活率為62.5%。我們的結論是男性乳癌病人平均年紀大於女性病人,也因此合併較多內科方面疾病。應衛教男性對於該疾病有更多的認知以期達到早期診斷。除了手術及放射線治療,接受輔助性全身性治療的病人較未接受者有存活上的好處。 |
英文摘要 | Objective: Male breast cancer is uncommon. It shares many similarities with breast cancer in women, but some differences exist. The purpose of this study is: 1) to investigate the experience of male breast cancers at Kaohsiung Chang Gung Memorial Hospital in the past 15 years, and 2) to review the literature with regard to male breast cancer. Methods: We retrospectively analyzed the records of male breast cancer collected from 1992 to 2006 at Kaohsiung Chang Gung Memorial Hospital. All the details of patient demographics, tumor characteristics, including histopathological diagnosis, treatment undertaken and outcomes were collected. Results: The mean age of the 24 male breast cancer patients was 62.4 years, and 10 of the patients had concurrent medical illness. Nineteen patients had a tumor larger than 2 cm. The majority of histopathologic diagnoses was infiltrating ductal carcinoma, and 15 out of the 19 patients (78.9%) had a hormone-receptor-positive disease. All patients underwent modified radical mastectomy, after which 10 patients received post-mastectomy irradiation therapy. Eighteen patients received adjuvant systemic therapy and achieved a 5-year survival rate of 81.3%, better than that for those who did not receive systemic therapy (40%). With a mean follow-up duration of 53.6 months, the breast cancer-specific 5-year survival rate was 71.4% and overall survival was 62.5%. Conclusions: The mean age of men with breast cancer was older than that in the female counterparts and consequently more medical co-morbidities were noted. Men should be made more aware of the disease to achieve an early diagnosis. In addition to surgery and radiation therapy, patients receiving adjuvant systemic therapy had more survival benefit than those who did not. |
本系統中英文摘要資訊取自各篇刊載內容。