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題名 | 山防風水萃物對小鼠體內免疫調節之研究=Studies on the In Vivo Immunomodulatory Properties of Echinops Grijsii Extract |
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作者 | 郭肇凱; 顏國欽; 許輔; 張隆仁; | 書刊名 | 臺中區農業改良場研究彙報 |
卷期 | 90 民95.03 |
頁次 | 頁41-50 |
分類號 | 414.52 |
關鍵詞 | 山防風; 免疫調節; 吞噬作用; 細胞增生; 免疫球蛋白; Echinops grijsii; Immunomodulatory function; Phagocytosis; Cell proliferation; Immunoglobulin; |
語文 | 中文(Chinese) |
中文摘要 | 試驗以BALB/c小鼠體內模式探討山防風水萃冷凍乾燥樣本所產生之免疫反應,結果體內非特異性免疫調節活性試驗發現,餵食山防風水萃冷凍乾燥樣本之小鼠單核球百分吞噬率可以顯著 (P<0.05) 高於餵食對照組;體內Ovalbumin (OVA) 特異性免疫調節活性試驗發現,餵食山防風水萃冷凍乾燥樣本之小鼠脾細胞,相較於餵食對照組會顯著 (P<0.05) 增加OVA特異性之脾細胞增生率,而且其血清相較於餵食對照組會產生顯著(P<0.05) OVA特異性之IgG生成,有助於體液防禦對抗侵害性之特異抗原。 |
英文摘要 | The objective of this study was to evaluate the immunomodulatory effects of Echinops grijsii extract in an in vivo experiments using BALB/c mice. The non-specific immunomodulatory experiments showed that administration of E. grijsii extract significantly (P<0.05) increased the phagocytosis percentage of monocytes. Besides, the OVA-specific immunomodulatory experiments showed that administration of E. grijsii extract not only significantly (P<0.05) enhanced the OVA-specific cell proliferation of mouse splenocytes but also stimulated OVA-specific IgG production significantly (P<0.05). It is speculated that the consumption of E. grijsii is useful for defending the invading specific antigens. |
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