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題 名 | Deep Vein Thrombosis Associated with Marked Hyperhomocysteinemia and Active Pulmonary Tuberculosis=深層靜脈栓塞病患合併高半胱銨酸血症及急性肺結核 |
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作 者 | 邱俊仁; 徐國基; | 書刊名 | Acta Cardiologica Sinica |
卷 期 | 23:3 2007.09[民96.09] |
頁 次 | 頁186-191 |
分類號 | 415.385 |
關鍵詞 | 深層靜脈栓塞; 高半胱銨酸血症; 肺結核; 葉酸缺乏; 高度凝血狀態; Deep vein thrombosis; Hyperhomocysteinemia; Pulmonary tuberculosis; Folic acid deficiency; Hypercoagulable state; |
語 文 | 英文(English) |
中文摘要 | 我們報告一位32歲之慢性腎功能不全 (chronic renal insufficiency) 病患同時發生急性肺結核及深層靜脈栓塞合併嚴重高半胱銨酸血症,葉酸缺乏 (folic acid deficiency),及凝血功能異常。深層靜脈栓塞經heparin治療後改善。半胱銨酸指數經葉酸及維它命B12補充後回復正常。月市結核亦於藥物治療後痊癒。此篇報告中,高半胱銨酸血症是由於葉酸缺乏及慢性腎功能不全造成的。 |
英文摘要 | We report a 32-year-old male patient presented with acute deep vein thrombosis of his right leg after recent onset of active pulmonary tuberculosis. Marked hyperhomocysteinemia (>50umol/L), folic acid deficiency, and abnormal coagulation profiles (elevations of fibrinogen and fibrinogen degradation product) were noted after a series of work-ups. After treatment with low-molecular-weight heparin, deep vein thrombosis improved. Serum homocysteine level returned to normal after folic acid and vitamin B12 supplementation for 2 months. After therapy with four-combined anti-tuberculosis drugs for 9 months, the pulmonary tuberculosis subsided. In the present case report, the cause of hyperhomocysteinemia may be related to folic acid deficiency and chronic renal insufficiency. |
本系統中英文摘要資訊取自各篇刊載內容。