查詢結果分析
來源資料
相關文獻
- Primary Sinonasal Mucosal Melanoma with Unusual Long-Term Survival
- Toward a Better Understanding of Sinonasal Mucosal Melanoma: Clinical Review of 23 Cases
- Primary Sinonasal Mucosal Malignant Melanoma--Case Report
- 以高張性鹽溶液激發鼻黏膜產生P物質之反應
- 以下鼻甲外觀變化鑑別診斷過敏性鼻炎及血管運動性鼻炎
- Endobronchial Metastatic Disease
- Cervical Lymph Node Metastasis from Melanoma of an Unknown Primary Site--Case Report
- Nodular Melanoma--A Thirteen-Year Clinical Experience
- 鼻腔及副鼻竇之惡性黑色素腫瘤
- Osteogenic Melanoma
頁籤選單縮合
題名 | Toward a Better Understanding of Sinonasal Mucosal Melanoma: Clinical Review of 23 Cases=原發性鼻竇黏膜黑色素瘤--23病例臨床回顧 |
---|---|
作者 | 鄭彥甫; 賴建仲; 何青吟; 許志宏; 林清榮; | 書刊名 | 中華醫學會雜誌 |
卷期 | 70:1 2007.01[民96.01] |
頁次 | 頁24-29+CA4 |
分類號 | 416.871 |
關鍵詞 | 黑色素瘤; 鼻黏膜; 鼻腫瘤; 鼻竇腫瘤; Melanoma; Nasal mucosa; Nasal neoplasm; Paranasal sinus neoplasm; |
語文 | 英文(English) |
中文摘要 | 背景:原發性鼻竇之黏膜黑色素瘤是一種罕見的疾病,其發生率遠低於表皮生的黑色素瘤。本研究回顧了原發顧鼻竇之黑色瘤,並分享此一罕見疾病之治療經驗。 方法:我們對1982年至2002年共23位在本院接受治療之鼻部及鼻竇黏膜黑色素瘤之病患,進行回溯性分析。結果:23名病患中,16名為男性,7名為女性;平均年齡68.2歲。在初認被診斷患病時,20名病患之黑色素瘤侷限在鼻竇局部,另外3名則已有遠端轉移之情況。治療之後,有6位病患發生局部復發,5位發生一頸部轉移,而有19位發生遠端轉移。5年存活率及局部控制率分別為22.26%及52.30。 結論。鼻部及鼻竇黏膜性黑色素瘤有很高的機率會從原發部位轉移出去。因此,預防全身性的轉移將改善整體存活率最重要的研究課題。 |
英文摘要 | Background: Primary sinonasal mucosal melanoma is a rare disease, occurring far less often than cutaneous lesions. The objective of this study was to review the records of patients diagnosed with primary sinonasal mucosal melanoma. Methods: We performed a retrospective review of the medical records of 23 patients with sinonasal mucosal melanoma who were treated at Taipei Veterans General Hospital between 1982 and 2002. Results: Sixteen of the 23 patients were male and 7 were female; their mean age was 68.2 years (range, 39–87 years). At diagnosis, the melanoma was limited to lesions located in the sinonasal area in 20 patients, and had spread in 3 patients. Local recurrence developed in 9 patients, neck metastasis in 5, and distant metastasis in 19. The 5-year disease-specific survival and local control rates were 22.26% and 52.30%, respectively. Conclusion: In our experience, primary sinonasal mucosa melanoma is prone to spread from the site of origin. The major obstacle in improving overall survival is achieving systemic control. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。