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相關文獻
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頁籤選單縮合
題 名 | Legionnaires' Disease in Community-Acquired Pneumonia Requiring Hospitalization in Taiwan=臺灣社區感染性肺炎需住院患者之退伍軍人病 |
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作 者 | 葉國明; 林永崇; 王甯祺; 張峰義; | 書刊名 | Journal of Medical Sciences |
卷 期 | 27:2 2007.04[民96.04] |
頁 次 | 頁63-66 |
分類號 | 415.4 |
關鍵詞 | 退伍軍人病; 社區感染性肺炎; Legionnaires' disease; Community-acquired pneumonia; |
語 文 | 英文(English) |
英文摘要 | Background: Legionnaires’ disease is a relatively common but underdiagnosed cause of pneumonia. This study was conducted to determine the incidence of Legionnaires’ disease in patients with community-acquired pneumonia (CAP). Methods: Three hundred and twenty-three consecutive patients with CAP admitted to a teaching hospital in Taiwan were studied. An indirect fluorescent antibody (IFA) for the detection of Legionella pneumophila serogroup 1-6 antibodies in serum and an enzyme immunoassay (EIA) for the detection of L. pneumophila serogroup 1 antigen in the urine were used for the diagnosis of Legionnaires’ disease. Results: Twenty-nine patients (9.0%) were diagnosed with Legionnaires’ disease. Among them, the male to female ratio was 20:9. Underlying risk factors and diseases included cigarette smoking (21%), chronic obstructive pulmonary disease (21%), disorders of the central nervous system (17%), diabetes mellitus (17%), and heart disease (17%). Fever (97%), cough (69%), hyponatremia (34%), elevated liver enzymes (24%), and gastrointestinal (24%) and neurological (21%) symptoms were common. Forty-eight percent of the patients were complicated by acute respiratory failure, and 3% by acute renal failure. The mortality rate of Legionnaires’ disease was 24%. The risk of mortality was higher in patients with hyponatremia, respiratory failure, and those aged over 70 years. Conclusions: Legionnaires’ disease should be investigated in patients with CAP requiring hospitalization in Taiwan. |
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